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减肥手术类型与阻塞性睡眠呼吸暂停、就业结果和身体形象满意度之间的关联:一项系统评价和荟萃分析

Associations between Type of Bariatric Surgery and Obstructive Sleep Apnoea, Employment Outcomes, and Body Image Satisfaction: A Systematic Review and Meta-Analysis.

作者信息

Leyaro Beatrice, Boakye Daniel, Howie Lyz, Ali Abdulmajid, Carragher Raymond

机构信息

School of Computing, Engineering and Physical Sciences, University of West of Scotland, Paisley, UK.

Institute of Public Health: Epidemiology and Biostatistics Department, Kilimanjaro Christian Medical University College, Moshi, Tanzania.

出版信息

Obes Facts. 2025;18(1):57-71. doi: 10.1159/000541782. Epub 2024 Oct 3.

Abstract

INTRODUCTION

Bariatric surgery has been shown to provide significant patient benefits in terms of weight loss and mitigation of obesity-linked comorbidities, as well as providing improvements in occupational productivity and patient quality of life. However, the choice of which bariatric surgery procedure provides the most patient benefit in each of these cases is still in question. In this review, we provide a systematic review, with the objective of evaluating associations between different bariatric surgery procedures and mitigation of obesity-linked comorbidities, improvement in occupational productivity, and patient quality of life, concentrating on three areas: obstructive sleep apnoea (OSA), employment prospects, and body image.

METHODS

The CINAHL, PubMed, Web of Science, and CENTRAL databases were searched for eligible studies. Summary risk ratio (RR) and 95% confidence intervals were estimated using random-effects models. Thirty-three studies were included in this review, including 29 cohort studies and 4 randomised clinical trials (RCTs).

RESULTS

Pooled analysis of the observational studies showed significantly lower OSA remission in sleeve gastrectomy (SG) compared to Roux-en-Y gastric bypass (RYGB) across both short-term (1-2 years) and longer term (3+ years) follow-up periods (RR = 0.91, 95% CI = 0.84-0.99, p = 0.02; and RR = 0.88, 95% CI = 0.65-0.99, p = 0.03, respectively). In contrast, a meta-analysis of the RCT studies found no difference in OSA remission between SG and RYGB (RR = 1.01, 95% CI = 0.81-1.25, p = 0.93). An analysis of four studies showed significantly higher OSA remission for SG versus adjustable gastric banding (RR = 1.83, 95% CI = 1.57-2.14, p < 0.001). No significant difference was observed regarding improvement in employment status between SG and RYGB (RR = 0.77, 95% CI = 0.32-1.87, p = 0.57). A narrative synthesis of studies on body image reported no significant differences between body image scores and surgery types.

CONCLUSION

This review found significantly lower OSA remission in SG as compared to RYGB across different follow-up periods, while no significant statistical difference was observed in RCT studies. Further studies are recommended to assess the effectiveness of the various bariatric surgeries in relation to improving employment status and body image, where primary studies are lacking.

摘要

引言

减肥手术已被证明能给患者带来显著益处,包括减轻体重、缓解与肥胖相关的合并症,以及提高职业生产力和患者生活质量。然而,在每种情况下,哪种减肥手术能为患者带来最大益处仍存在疑问。在本综述中,我们进行了一项系统综述,目的是评估不同减肥手术与缓解肥胖相关合并症、提高职业生产力和患者生活质量之间的关联,重点关注三个方面:阻塞性睡眠呼吸暂停(OSA)、就业前景和身体形象。

方法

在CINAHL、PubMed、科学网和CENTRAL数据库中检索符合条件的研究。使用随机效应模型估计汇总风险比(RR)和95%置信区间。本综述纳入了33项研究,包括29项队列研究和4项随机临床试验(RCT)。

结果

观察性研究的汇总分析显示,在短期(1 - 2年)和长期(3年以上)随访期内,与Roux - en - Y胃旁路术(RYGB)相比,袖状胃切除术(SG)的OSA缓解率显著更低(RR = 0.91,95% CI = 0.84 - 0.99,p = 0.02;以及RR = 0.88,95% CI = 0.65 - 0.99,p = 0.03)。相比之下,RCT研究的荟萃分析发现SG和RYGB之间的OSA缓解率没有差异(RR = 1.01,95% CI = 0.81 - 1.25,p = 0.93)。对四项研究的分析显示,SG的OSA缓解率显著高于可调节胃束带术(RR = 1.83,95% CI = 1.57 - 2.14,p < 0.001)。SG和RYGB在就业状况改善方面未观察到显著差异(RR = 0.77,95% CI = 0.32 - 1.87,p = 0.57)。关于身体形象的研究的叙述性综合分析报告称,身体形象评分与手术类型之间没有显著差异。

结论

本综述发现,在不同随访期内,SG的OSA缓解率显著低于RYGB,而在RCT研究中未观察到显著统计学差异。鉴于缺乏初步研究,建议进一步开展研究,以评估各种减肥手术在改善就业状况和身体形象方面的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/421b/12017764/ab5cca4a5936/ofa-2025-0018-0001-541782_F01.jpg

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