Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Statistics, Kyungpook National University, Daegu, Republic of Korea.
Sci Rep. 2024 Oct 3;14(1):22955. doi: 10.1038/s41598-024-74205-x.
Early peritoneal dialysis (PD)-related infection is a severe complication. This study investigated the relationship between patient-doctor contact (PDC) duration and early PD-related infection. In the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) Korea, incident dialysis patients receiving PD were divided into two groups based on PDC duration (< 15 min versus ≥ 15 min), which was defined as the duration a nephrologist typically spends with a patient receiving PD during each visit according to the facility practice pattern. Early risks of PD-related infections, such as peritonitis and catheter-related infection (onset within 3 and 12 months of PD), were compared to the PDC duration using Cox regression. The study included 276 patients (184 [66.7%] in the shorter PDC group [< 15 min] and 92 [33.3%] in the longer PDC group [≥ 15 min]). The average age did not differ between the groups. The incidences of 3- and 12-month PD-related infections were significantly lower in the longer PDC group than in the shorter PDC group (3 months: 1.1% versus 9.8%, P = 0.007; 12 months: 9.8% versus 23.4%, P = 0.007). Longer PDC was independently associated with a lower risk of PD-related infections at 3 and 12 months (3 months: adjusted hazard ratio [aHR], 0.11; 95% confidence interval [CI], 0.02-0.85, P = 0.034; 12 months: aHR, 0.43; 95% CI 0.19-0.99, P = 0.048). Overall, a longer PDC duration was associated with a significantly lower risk of early PD-related infection.
早期腹膜透析（PD）相关感染是一种严重的并发症。本研究探讨了患者-医生接触（PDC）时间与早期 PD 相关感染之间的关系。在韩国腹膜透析结局和实践模式研究（PDOPPS Korea）中，接受 PD 的新透析患者根据 PDC 时间分为两组（<15 分钟与≥15 分钟），根据机构实践模式，PDC 时间定义为每位接受 PD 的患者每次就诊时，肾病医生通常与患者相处的时间。使用 Cox 回归比较了 PD 相关感染（腹膜炎和导管相关感染，在 PD 开始后 3 个月和 12 个月内发生）的早期风险与 PDC 时间之间的关系。该研究纳入了 276 名患者（184 名（66.7%）患者的 PDC 时间较短（<15 分钟），92 名（33.3%）患者的 PDC 时间较长（≥15 分钟））。两组的平均年龄无差异。较长 PDC 组的 3 个月和 12 个月 PD 相关感染发生率明显低于较短 PDC 组（3 个月：1.1%比 9.8%，P=0.007；12 个月：9.8%比 23.4%，P=0.007）。较长的 PDC 与 3 个月和 12 个月时 PD 相关感染的风险降低独立相关（3 个月：调整后的危险比[aHR]，0.11；95%置信区间[CI]，0.02-0.85，P=0.034；12 个月：aHR，0.43；95%CI 0.19-0.99，P=0.048）。总体而言，较长的 PDC 时间与早期 PD 相关感染的风险显著降低相关。
