Suppr超能文献

经皮椎间孔与骶管注射靶向治疗腰椎神经根病的临床效果和体格检查比较:一项单盲随机临床试验。

Comparison of Clinical Effects and Physical Examination of Transforaminal and Caudal Steroid Injection With Targeted Catheter in Lumbar Radiculopathy: A Single-Blind Randomized Clinical Trial.

机构信息

Pain Research Center, Department of Anesthesiology and Pain Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Brain Behav. 2024 Oct;14(10):e70067. doi: 10.1002/brb3.70067.

Abstract

BACKGROUND

Transforaminal and caudal epidural injections are two methods of steroid injection in lumbar radiculopathy. Using a targeted catheter with the possibility of accessing the involved spinal roots and steroid administration selectively next to them during the caudal procedure may achieve the benefits of both transforaminal and caudal procedures. The aim of this study was to investigate the clinical effects and physical examinations of transforaminal steroid injection compared to caudal through a targeted catheter in lumbar radiculopathy.

METHODS

Fifty patients with lumbar radiculopathy candidates for epidural steroid injection were divided into transforaminal (T) and caudal (C) groups. Steroid injection under fluoroscopic guidance was performed in group T with the transforaminal method and in group C with the caudal method using a targeted catheter for each involved spinal nerve root. Pain intensity visual analog scale (VAS), Oswestry Disability Index (ODI), daily analgesic consumption, and physical examinations on four follow-ups (before injection, second week, first and third month) were evaluated.

RESULTS

Pain score (VAS) and functional disability index (ODI) were similar in both groups, and there was no significant difference between the two groups (p > 0.05). The positive Lasègue test was significantly higher in the caudal group than in the transforaminal group only in the third month (p < 0.05). Other physical examinations in both groups did not have significant differences in all the follow-ups. Moreover, there was no difference in the amount of analgesic consumption in the two groups. No complications were observed in both groups.

CONCLUSION

This study showed that transforaminal and caudal steroid injection (with a targeted catheter) in patients with lumbar radiculopathy had similar effects in controlling pain and improving functional disability of patients in the short term. Cases of recurrence of positive Lasègue test in physical examinations in the long term (third month) in the caudal group may indicate the preference of the transforaminal approach.

TRIAL REGISTRATION

Iranian Registry of Clinical Trials (IRCT) number: IRCT20111102007984N31.

摘要

背景

经椎间孔和骶管硬膜外注射是治疗腰椎神经根病的两种类固醇注射方法。在骶管程序中使用带有靶向导管的方法,使其有可能接近受累的脊神经根,并在其旁边进行选择性类固醇给药,可能会同时获得经椎间孔和骶管程序的益处。本研究旨在比较腰椎神经根病患者经椎间孔和靶向导管骶管硬膜外类固醇注射的临床效果和体格检查。

方法

50 名腰椎神经根病患者符合硬膜外类固醇注射标准,分为经椎间孔(T)组和骶管(C)组。T 组采用经椎间孔方法,C 组采用靶向导管骶管方法,在透视引导下进行类固醇注射。在四个随访时间点(注射前、第二周、第一个月和第三个月)评估疼痛强度视觉模拟量表(VAS)、Oswestry 残疾指数(ODI)、每日镇痛药消耗量和体格检查。

结果

两组的疼痛评分(VAS)和功能障碍指数(ODI)相似,两组之间无显著差异(p>0.05)。仅在第三个月,骶管组的 Lasègue 试验阳性率明显高于经椎间孔组(p<0.05)。两组在所有随访中其他体格检查均无显著差异。此外,两组镇痛药消耗量无差异。两组均未观察到并发症。

结论

本研究表明,对于腰椎神经根病患者,经椎间孔和骶管(使用靶向导管)类固醇注射在短期内控制疼痛和改善患者功能障碍方面具有相似的效果。在长期(第三个月)体格检查中出现 Lasègue 试验阳性率复发现象的骶管组病例可能表明经椎间孔入路更具优势。

试验注册

伊朗临床试验注册中心(IRCT)编号:IRCT20111102007984N31。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b83/11450248/1c10f3e43cc7/BRB3-14-e70067-g002.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验