[Digestive and cutaneous colonization of Staphylococcus aureus, Pseudomonas aeruginosa and Corynebacterium xerosis in germ-free hairless mice].

Regardless of the method of germ-free HRS mouse contamination, the kinetics of Staphylococcus aureus and Pseudomonas aeruginosa cutaneous colonization was parallel to the kinetics of intestinal colonization; Corynebacterium xerosis, however, was unable to colonize the skin or the gastrointestinal tract. There was little variability in intestinal and cutaneous colonization; this was quite different from observations in man and hairless holoxenic mice. It is possible to use these experimental models to standardize the measurement of antiseptic bactericidal activity in vivo.