Shaligram Ruhi, Malwade Sudhir, Garud Balakrushna P, Mane Shailaja
Pediatrics, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, IND.
Cureus. 2024 Sep 3;16(9):e68548. doi: 10.7759/cureus.68548. eCollection 2024 Sep.
Infantile hypertrophic pyloric stenosis (IHPS) is a condition typically characterized by hypertrophy of the pylorus, leading to gastric outlet obstruction and forceful, nonbilious vomiting in young infants. This case series reports two infants with IHPS who exhibited metabolic acidosis, deviating from the classical biochemical presentation of hypochloremic, hypokalemic metabolic alkalosis. The unusual occurrence of metabolic acidosis in these cases suggests the possibility of alternative or additional pathophysiological mechanisms at play. Such deviations from the expected biochemical profile highlight the complexity of IHPS and the need for a broader diagnostic perspective.
婴儿肥厚性幽门狭窄(IHPS)是一种通常以幽门肥厚为特征的病症,导致胃出口梗阻,并在幼儿中引起强力的、非胆汁性呕吐。本病例系列报告了两名患有IHPS的婴儿,他们表现出代谢性酸中毒,这与低氯性、低钾性代谢性碱中毒的经典生化表现不同。这些病例中代谢性酸中毒的异常发生提示可能存在其他或额外的病理生理机制在起作用。这种与预期生化特征的偏差凸显了IHPS的复杂性以及需要更广泛的诊断视角。