Ayoobkhan Fathima Shehnaz, Padmanabhan Dakshin S, Mahayni Rula, Riaz Sara, Krishnamoorthy Geetha
Internal Medicine, Trinity Health Oakland Hospital, Pontiac, USA.
Infectious Disease, Trinity Health Oakland Hospital, Pontiac, USA.
Cureus. 2024 Sep 3;16(9):e68549. doi: 10.7759/cureus.68549. eCollection 2024 Sep.
Acquired hemophilia A (AHA) is characterized by the development of neutralizing autoantibodies, called "inhibitors," against intrinsic factor VIII. Its presentation differs profoundly from congenital hemophilia. Here, we present the case of a 69-year-old patient presenting with right-sided flank pain and hematuria, initially diagnosed with acute pyelonephritis, who was found to have bilateral renal hemorrhage during the course of his hospitalization. Later, after a thorough diagnostic evaluation, he was deemed to have AHA.
获得性血友病A(AHA)的特征是产生针对内源性凝血因子VIII的中和性自身抗体,即“抑制剂”。其临床表现与先天性血友病有很大不同。在此,我们报告一例69岁患者,该患者以右侧胁腹疼痛和血尿就诊,最初被诊断为急性肾盂肾炎,在住院期间发现双侧肾出血。后来,经过全面的诊断评估,他被诊断为AHA。