Atilan Kubra, Ozdem Tayfun, Aydogan Canset Nur, Hosbul Tugrul
Clinic of Medical Microbiology, Gülhane Training and Research Hospital, University of Health Sciences, Ankara, 06010, Türkiye.
Department of Cardiovascular Surgery, Gülhane Training and Research Hospital, University of Health Sciences, Ankara, 06010, Türkiye.
Folia Microbiol (Praha). 2025 Feb;70(1):249-252. doi: 10.1007/s12223-024-01203-x. Epub 2024 Oct 4.
In 2019, Pantoea piersonii was initially isolated from the interior surfaces of the International Space Station. This microorganism is a species within the genus Pantoea in the family Erwiniaceae, belonging to the order Enterobacterales. Recent literature has documented four cases of its isolation. Despite initial predictions suggesting the non-pathogenicity of P. piersonii strains, evidence from observed cases indicates potential pathogenicity. According to documented evidence in the literature, this microorganism is capable of causing severe and life-threatening conditions, including sepsis. Traditional tests, as well as automated systems, may fail to provide complete differentiation due to these similarities. While MALDI-TOF MS is a valuable tool for identification in clinical diagnostic microbiology, sequencing may be necessary for precise identification. To determine the antibiotic susceptibility profile, various methods can be utilized, including minimum inhibitory concentration determination, disk diffusion testing (Kirby-Bauer test), genotypic resistance assays (PCR and sequencing), and automated systems. The literature reports a limited number of cases associating P. piersonii with human infection. This study contributes to this body of knowledge by reporting a novel case in which P. piersonii was isolated from a tissue sample for the first time. In this case report, the patient achieved recovery following the administration of appropriate antibiotic treatment based on the diagnosis. It underscores the need for precise identification and understanding of its pathogenicity.
2019年，皮尔逊泛菌最初是从国际空间站的内表面分离出来的。这种微生物是欧文氏菌科泛菌属中的一个物种，属于肠杆菌目。最近的文献记录了4例其分离情况。尽管最初的预测表明皮尔逊泛菌菌株无致病性，但观察到的病例证据表明其具有潜在致病性。根据文献中的记录证据，这种微生物能够引发严重且危及生命的状况，包括败血症。由于这些相似性，传统检测方法以及自动化系统可能无法提供完全的区分。虽然基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）是临床诊断微生物学中用于鉴定的一种有价值的工具，但可能需要测序才能进行精确鉴定。为了确定抗生素敏感性谱，可以采用多种方法，包括最低抑菌浓度测定、纸片扩散试验（Kirby-Bauer试验）、基因型耐药性检测（PCR和测序）以及自动化系统。文献报道与皮尔逊泛菌相关的人类感染病例数量有限。本研究通过报告首例从组织样本中分离出皮尔逊泛菌的新病例，为这一知识体系做出了贡献。在本病例报告中，患者在根据诊断给予适当抗生素治疗后实现了康复。它强调了精确鉴定并了解其致病性的必要性。
