Friedman M J, Kalbfleisch J M, Robins L, McEntee C W, Brewer D L, Slagle R C, O'Meara B, Hall R, Conrad L L, Hawkins H M
Cardiol Clin. 1985 Feb;3(1):85-91.
Intracoronary streptokinase administration has been an effective procedure for establishing reperfusion of an evolving myocardial infarction by lysing the thrombus that is usually responsible for the infarction. After reperfusion is accomplished, appropriate management of the patient must be planned to provide the best chance for assuring continued vessel patency, and appropriate management of the patient's residual coronary artery disease also must be considered. In selected patients, percutaneous transluminal coronary angioplasty of the residual coronary lesion has been performed successfully immediately following reperfusion with streptokinase. Early coronary artery bypass graft surgery has been performed with good results in other patients. The appropriate management of the patient with acute myocardial infarction is still evolving, and only with additional study and experience will the "best" approach in the management of these patients be defined.
冠状动脉内注射链激酶一直是通过溶解通常导致梗死的血栓来建立进展性心肌梗死再灌注的有效方法。再灌注完成后，必须规划对患者的适当管理，以提供确保血管持续通畅的最佳机会，同时也必须考虑对患者残余冠状动脉疾病的适当管理。在选定的患者中，在链激酶再灌注后立即成功地对残余冠状动脉病变进行了经皮腔内冠状动脉成形术。在其他患者中，早期冠状动脉搭桥手术也取得了良好效果。急性心肌梗死患者的适当管理仍在不断发展，只有通过更多的研究和经验，才能确定这些患者管理中的“最佳”方法。
