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老挝人民民主共和国有望消除湄公血吸虫病:最后一位重症患者?

Elimination of schistosomiasis mekongi in reach for Lao PDR: The last patient with severe disease?

作者信息

Southisavath Phonesavanh, Kling Kerstin, Homsana Anousin, Probst-Hensch Nicole, Paris Daniel Henry, Sayasone Somphou, Odermatt Peter

机构信息

Lao Tropical and Public Health Institute, Vientiane, Laos; Swiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland; Department of Radiology, Mahosot Hospital, Vientiane, Laos.

Department of Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.

出版信息

Parasitol Int. 2025 Feb;104:102976. doi: 10.1016/j.parint.2024.102976. Epub 2024 Oct 2.

Abstract

Schistosomiasis mekongi is endemic in a restricted area in Northern Cambodia and the Southern Lao People's Democratic Republic. Severe hepatobiliary morbidity is associated with chronic untreated S. mekongi infection. Since the 1980s extensive control efforts have been employed in endemic areas, resulting in substantial reduction of infection rates and disease burden. We report on a patient with a fatal course of clinically-assessed chronic schistosomiasis. This report underscores that patients with severe chronic Mekong schistosomiasis may still exist and may need treatment support.

摘要

湄公血吸虫病在柬埔寨北部和老挝人民民主共和国南部的一个受限区域呈地方性流行。严重的肝胆疾病与未经治疗的慢性湄公血吸虫感染有关。自20世纪80年代以来,流行地区已开展了广泛的防治工作,使感染率和疾病负担大幅降低。我们报告了一例经临床评估为慢性血吸虫病且病程致命的患者。本报告强调,严重慢性湄公血吸虫病患者可能仍然存在,可能需要治疗支持。

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