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“惊恐障碍”。临床及生物学关联因素。

"Panic-attack disorders". Clinical and biological correlates.

作者信息

Deltito J A, Cassano G B

出版信息

Encephale. 1985 Jul-Aug;11(4):163-5.

PMID:3936695
Abstract

A large group of patients suffer anxiety and phobic disorders which although are somewhat difficult to separate from other nosologic entities solely on clinical grounds, are having their borders with these disorders more keenly defined through our increased knowledge regarding various biological correlates. The main biological correlates: family history, incidence of mitral valve prolapse, response to specific pharmacological therapies, and provocation of panic attacks through the administration of I.V. sodium lactate is reviewed. Focus is placed on a current hypothesis regarding the mechanism of action of lactate infusion.

摘要

一大群患者患有焦虑症和恐惧症,尽管仅根据临床依据将其与其他疾病实体区分开来有些困难,但随着我们对各种生物学关联的了解不断增加,它们与这些疾病的界限正被更清晰地界定。主要的生物学关联包括:家族病史、二尖瓣脱垂的发生率、对特定药物治疗的反应以及静脉注射乳酸钠引发惊恐发作的情况都将进行综述。重点是关于乳酸输注作用机制的当前假说。

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