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美国因呼吸道合胞病毒感染住院的成年人出院后的即时护理。

Immediate post-discharge care among US adults hospitalized with respiratory syncytial virus infection.

机构信息

Value & Evidence, Pfizer Inc, Collegeville, PA, 19426, USA.

Evidence Generation RWE team, Pfizer Inc, remote, MD, USA.

出版信息

BMC Pulm Med. 2024 Oct 4;24(1):486. doi: 10.1186/s12890-024-03251-y.

Abstract

BACKGROUND

Respiratory Syncytial Virus (RSV) is an important pathogen causing acute respiratory illnesses in adults. RSV infection can lead to severe outcomes, including hospitalizations and even death. Despite the increased recognition of the burden in older adults, immediate post-discharge care needs among adults hospitalized with RSV are not well characterized and have not been compared to other serious medical conditions (such as influenza, acute myocardial infarction (MI), and stroke) for which there have been long-standing disease prevention efforts.

OBJECTIVES

This study aims to describe the immediate post-discharge care needs among adults hospitalized with RSV in the United States and descriptively compare it to those hospitalized with influenza, acute MI, or stroke.

DESIGN

Retrospective observational cohort study.

PATIENTS

Adults aged ≥ 18 years, hospitalized with a primary diagnosis of RSV, influenza, acute MI, or stroke from January 01, 2016, to December 31, 2019, were identified from the Premier Healthcare Database using the International Classification of Diseases (ICD-10) codes.

MAIN MEASURES

Immediate post-discharge care was categorized into three different levels of care based on the discharge dispositions. Descriptive analyses were performed.

KEY RESULTS

In total, 3,629 RSV, 303,577 influenza, 388,682 acute MI, and 416,750 stroke hospitalizations were identified, the majority occurred among patients aged ≥ 65 years. Professional home care needs were the highest for RSV hospitalizations (19.1%), followed by influenza (17.7%), stroke (15.4%), and acute MI (9.8%). Additionally, institutional care needs immediately following discharge were similar for RSV, influenza, and acute MI hospitalizations (14.2%, 15.8%, and 14.1%, respectively).

CONCLUSIONS

Immediate post-discharge care needs among adults hospitalized with RSV, especially in older adults, can be considerable and comparable to influenza and acute MI discharges. With recently approved RSV vaccines, efforts to increase vaccination in older adults are needed to prevent RSV and associated healthcare consequences.

摘要

背景

呼吸道合胞病毒(RSV)是导致成人急性呼吸道疾病的重要病原体。RSV 感染可导致严重后果,包括住院治疗,甚至死亡。尽管人们越来越认识到老年人的负担,但住院治疗的 RSV 成人患者的出院后即时护理需求尚未得到充分描述,也未与其他严重疾病(如流感、急性心肌梗死(MI)和中风)进行比较,后者的疾病预防工作已经有很长的历史。

目的

本研究旨在描述美国住院治疗的 RSV 成人患者的出院后即时护理需求,并对其与流感、急性 MI 或中风住院患者进行描述性比较。

设计

回顾性观察性队列研究。

患者

从 Premier Healthcare Database 中使用国际疾病分类(ICD-10)代码,于 2016 年 1 月 1 日至 2019 年 12 月 31 日期间确定年龄≥18 岁、患有 RSV、流感、急性 MI 或中风的原发性诊断的住院患者。

主要措施

根据出院处置,将出院后护理分为三个不同级别的护理。进行描述性分析。

主要结果

共确定了 3629 例 RSV、303577 例流感、388682 例急性 MI 和 416750 例中风住院患者,大多数患者年龄≥65 岁。专业家庭护理需求最高的是 RSV 住院患者(19.1%),其次是流感(17.7%)、中风(15.4%)和急性 MI(9.8%)。此外,RSV、流感和急性 MI 住院患者出院后立即需要机构护理的比例相似(分别为 14.2%、15.8%和 14.1%)。

结论

住院治疗的 RSV 成人患者,尤其是老年患者,出院后即时护理需求相当大,与流感和急性 MI 出院患者相当。随着最近批准的 RSV 疫苗,需要努力增加老年人的疫苗接种,以预防 RSV 和相关的医疗后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81ef/11451113/cbd17d3b9bfa/12890_2024_3251_Fig1_HTML.jpg

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