Alqanas Sarah, Alsahiem Jood, Aljami Abdullah, Alsudairi Nourah, Ahmad Shakil, Sharma Sonali, Rajinder Sumit, Alamri Abdulaziz, Alhazmi Hesham, Hegazi Fahad
College of Dentistry, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
AEGD Resident, Riyadh Second Health Cluster, Riyadh, Saudi Arabia.
Int J Paediatr Dent. 2025 May;35(3):625-638. doi: 10.1111/ipd.13273. Epub 2024 Oct 4.
Dental caries and molar-incisor hypomineralization (MIH) are primary reasons for the extraction of first permanent molars (M1) in children, which can lead to significant dental and facial development issues such as a midline shift and temporomandibular joint disorder.
This systematic review aimed to identify key factors influencing spontaneous space closure following the early extraction of first permanent molars (M1) in children aged 5-15.
We conducted a comprehensive search across Scopus, PubMed, Dimensions, Web of Science, and Cochrane databases, including the literature from 1960 to 2024. The inclusion criteria focused on clinical trials, case-control, cross-sectional, cohort studies, and case series that evaluated the impact of various factors on the spontaneous closure after M1 extraction.
The analysis highlights that chronological age and the developmental stage of the second permanent molars (M2) at the time of extraction are significant predictors of successful spontaneous space closure. Additionally, the presence and angle of M2, along with the presence of third permanent molars (M3), play crucial roles but require further investigation.
Early assessment of M2's developmental stage and inclination, and the presence of M3 are essential for enhancing the likelihood of successful spontaneous space closure following M1 extraction in children.
龋齿和第一恒磨牙矿化不全（MIH）是儿童第一恒磨牙（M1）拔除的主要原因，这可能导致严重的牙齿和面部发育问题，如中线偏移和颞下颌关节紊乱。
本系统评价旨在确定影响5至15岁儿童早期拔除第一恒磨牙（M1）后自发间隙关闭的关键因素。
我们在Scopus、PubMed、Dimensions、科学网和考克兰数据库中进行了全面检索，包括1960年至2024年的文献。纳入标准侧重于评估各种因素对M1拔除后自发关闭影响的临床试验、病例对照、横断面、队列研究和病例系列。
分析表明，年龄和拔除时第二恒磨牙（M2）的发育阶段是自发间隙成功关闭的重要预测因素。此外，M2的存在和角度以及第三恒磨牙（M3）的存在起着关键作用，但需要进一步研究。
早期评估M2的发育阶段和倾斜度以及M3的存在对于提高儿童M1拔除后自发间隙成功关闭的可能性至关重要。
