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儿童第一恒磨牙拔除——历史、目的、间隙关闭及其他后果的综合综述

Extraction of First Permanent Molars in Children-A Comprehensive Review of History, Aim, Space Closure and Other Consequences.

作者信息

Masri Ahmad Al, Mourad Mhd Said, Splieth Christian H, Krey Karl-Friedrich, Schmoeckel Julian

机构信息

Department of Pediatric Dentistry, University Medicine Greifswald, Walther-Rathenau-Str 42a, 17489 Greifswald, Germany.

Department of Orthodontics, University Medicine Greifswald, Walther-Rathenau-Str 42a, 17489 Greifswald, Germany.

出版信息

J Clin Med. 2025 Mar 25;14(7):2221. doi: 10.3390/jcm14072221.

DOI:10.3390/jcm14072221
PMID:40217671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11989315/
Abstract

Compromised first permanent molars (FPMs) in children pose major challenges for dentists and patients even in low-caries-risk populations. Whether due to caries or Molar Incisor Hypomineralization (MIH), compromised FPMs at an early age require careful treatment planning and timing of extraction, if necessary, to eventually have good space closure with healthy dentition. This comprehensive review explains the concept of early extraction of the FPMs in children and lists the results of published studies and systematic reviews regarding spontaneous or orthodontical space closure after the extraction of an FPM, including its consequences in the long term. In general, the majority of the studies confirm that spontaneous space closure after the early extraction of the maxillary FPM could be achieved if the extraction is performed before the eruption of the second permanent molar (SPM). On the other hand, space closure in the mandible is possible in case of optimal timing of extraction and supporting co-factors, but in practice, it would most probably require orthodontic treatment. The decision to retain or extract compromised FPMs must always be made on an individual basis, taking into account all relevant factors and the long-term effects on the entire stomatognathic system. Early prophylaxis to prevent caries and early management of MIH-affected FPMs should, however, be the first-line approach.

摘要

即使在低患龋风险人群中,儿童第一恒磨牙(FPMs)受损也给牙医和患者带来了重大挑战。无论是由于龋齿还是磨牙切牙矿化不全(MIH),早期受损的FPMs都需要仔细的治疗计划以及必要时拔牙的时机选择,以便最终能利用健康的牙列实现良好的间隙关闭。这篇综述解释了儿童FPMs早期拔牙的概念,并列出了已发表的研究结果以及关于FPMs拔除后自发或正畸间隙关闭的系统评价,包括其长期后果。总体而言,大多数研究证实,如果在上颌第二恒磨牙(SPM)萌出之前进行拔牙,上颌FPMs早期拔除后可实现自发间隙关闭。另一方面,在下颌,拔牙时机和辅助因素合适时间隙关闭是可能的,但在实际操作中,很可能需要正畸治疗。保留或拔除受损FPMs的决定必须始终基于个体情况,考虑所有相关因素以及对整个口颌系统的长期影响。然而,预防龋齿的早期预防措施和对受MIH影响的FPMs的早期管理应作为一线方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2713/11989315/b86e91113e01/jcm-14-02221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2713/11989315/b86e91113e01/jcm-14-02221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2713/11989315/b86e91113e01/jcm-14-02221-g001.jpg

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本文引用的文献

1
Spontaneous space closure after extraction of young first permanent molar. Retrospective cohort study.年轻第一恒磨牙拔除后的自发性间隙关闭。回顾性队列研究。
PeerJ. 2024 Oct 23;12:e18276. doi: 10.7717/peerj.18276. eCollection 2024.
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Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review and meta-analysis.儿童和青少年第一恒磨牙拔除后自发性间隙关闭的系统评价和荟萃分析。
Eur J Orthod. 2024 Dec 1;46(6). doi: 10.1093/ejo/cjae054.
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Factors related to spontaneous space closure following early first permanent molar extraction: A systematic review.
早期拔除第一恒磨牙后自发间隙关闭的相关因素:一项系统评价
Int J Paediatr Dent. 2025 May;35(3):625-638. doi: 10.1111/ipd.13273. Epub 2024 Oct 4.
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Timing for extraction of permanent first molars in school aged children: a pilot study.学龄儿童中第一恒磨牙拔除时机的研究:一项初步研究。
J Clin Pediatr Dent. 2024 Jan;48(1):78-84. doi: 10.22514/jocpd.2024.010. Epub 2024 Jan 3.
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Treatment outcomes of regenerative endodontic therapy in immature permanent teeth with pulpal necrosis: A systematic review and network meta-analysis.牙髓坏死未成熟恒牙再生性内根治疗的疗效:系统评价和网络荟萃分析。
Int Endod J. 2024 Mar;57(3):238-255. doi: 10.1111/iej.13999. Epub 2023 Nov 15.
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Eruption Pattern of Third Molars in Orthodontic Patients Treated with First Permanent Molar Extraction: A Longitudinal Retrospective Evaluation.拔除第一恒磨牙正畸治疗患者第三磨牙的萌出模式:一项纵向回顾性评估
J Clin Med. 2023 Jan 30;12(3):1060. doi: 10.3390/jcm12031060.
7
The impact of the loss of first permanent molars on the duration of treatment in patients treated with orthodontic space closure and without skeletal anchorage.第一恒磨牙缺失对无骨支抗的正畸关闭间隙治疗患者疗程的影响。
Prog Orthod. 2022 Sep 12;23(1):32. doi: 10.1186/s40510-022-00427-2.
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Should compromised first permanent molar teeth in children be routinely removed? A health economics analysis.儿童受损的第一恒磨牙是否应常规拔除?一项健康经济学分析。
Community Dent Oral Epidemiol. 2023 Oct;51(5):755-766. doi: 10.1111/cdoe.12751. Epub 2022 May 31.
9
Radiographic Evaluation of Permanent Second Molar Substitution After Extraction of Permanent First Molar: Identifying Predictors for Spontaneous Space Closure.第一恒磨牙拔除后第二恒磨牙替代的影像学评估:确定自发间隙关闭的预测因素。
Pediatr Dent. 2022 Mar 15;44(2):123-130.
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Spontaneous space closure following the extraction of the first permanent mandibular molar.拔除下颌第一恒磨牙后的自发性间隙关闭。
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