Fermentation production of L-homoserine by Corynebacterium sp. and its possible use in the preparation of threonine and lysine.

A mutant Corynebacterium sp. requiring threonine and cultivated for 3 d in a medium containing 15% sucrose, 8% corn-steep and 50 micrograms biotin per litre accumulated 14.5 g L-homoserine per litre. The possibility of fermenting the homoserine obtained for threonine and lysine production was investigated.