Baldas J, Bonnyman J
Int J Appl Radiat Isot. 1985 Dec;36(12):919-23. doi: 10.1016/0020-708x(85)90247-9.
The preparation of the 99mTcN-complexes of gluconate, EHDP, HIDA and PIPIDA by substitution reactions of 99mTcNCl4- is described. Studies of the distribution of these complexes in mice indicate that the presence of the Tc-nitrido group significantly alters the biological properties of the 99mTc-complexes formed using these ligands. Results suggest that the 99mTcN-complexes of these ligands are labile and undergo some ligand exchange in vivo.
描述了通过(^{99m}TcNCl_4^-)的取代反应制备葡萄糖酸盐、EHDP、HIDA和PIPIDA的(^{99m}TcN)配合物。这些配合物在小鼠体内分布的研究表明，锝-氮基的存在显著改变了使用这些配体形成的(^{99m}Tc)配合物的生物学性质。结果表明，这些配体的(^{99m}TcN)配合物不稳定，在体内会发生一些配体交换。
