锝放射性药物的化学。I. 使用载体⁹⁹Tc探索锝（IV）在葡萄糖酸锝-锡和羟基亚乙基二膦酸锝-锡中的组织分布及氧化态影响。
Chemistry of technetium radiopharmaceuticals. I. Exploration of the tissue distribution and oxidation state consequences of technetium (IV) in Tc-Sn-gluconate and Tc-Sn-EHDP using carrier 99Tc.
作者信息
Hambright P, McRae J, Valk P E, Bearden A J, Shipley B A
出版信息
J Nucl Med. 1975 Jun;16(6):478-82.
PMID:808594
Abstract
The distribution in rats of the renal agent Tc-Sn-gluconate using both 99mTc and carrier amounts of 99Tc was similar. The same behavior was shown with the bone agent Tc-Sn-EHDP. The radiopharmaceutical consequences of the observed Tc(IV) oxidation state in these systems are explored.
摘要
使用99mTc和99Tc载体量时，肾显像剂锝-锡-葡萄糖酸盐在大鼠体内的分布相似。骨显像剂锝-锡-亚甲基二膦酸盐也表现出相同的行为。本文探讨了在这些体系中观察到的Tc(IV)氧化态对放射性药物的影响。
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