Faraji Navid, Pourbahram Raheleh, Goli Rasoul, Parvaresh Banafsheh, Alidoust Hassan, Dastgerdi Maryam Ebrahimi
Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Urmia University of Medical Sciences, Nursing and Midwifery Faculty, Campus Nazlu, 11 KM Road Seru, Urmia, West Azerbaijan, Iran.
Department of Critical Care Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tajrish Velenjak 7th Floor, Bldg No.2 SBUMS, Arabi Ave., Tehran 1983969411, Tehran Province, Iran.
Int J Surg Case Rep. 2024 Nov;124:110378. doi: 10.1016/j.ijscr.2024.110378. Epub 2024 Oct 1.
Squamous cell carcinoma (SCC) is a cancerous tumor that can develop when normal keratinocytes undergo a transformation into invasive cancer cells, typically due to genetic mutations that affect cell growth and differentiation. SCC is frequently found on sun-exposed areas of the skin like the face, ears, neck, and hands, but it is unusual to see it develop on the soles of the feet.
This case is about a 22-year-old man who came in with a persistent sore on the bottom of his left foot. The patient mentioned sustaining a small injury to his foot about two weeks before seeking medical help, which started off as a minor wound but deteriorated over time. Ultimately, the diagnosis revealed squamous cell carcinoma that had spread to the lungs and lymph nodes.
This case highlights the importance of considering the possibility of malignancy in non-healing wounds, even in young patients without known risk factors. The initial presentation of a simple sore that progressed to metastatic SCC underscores the challenges in diagnosing and managing skin cancers in atypical presentations.
This case highlights cancer's aggressiveness and atypical youth presentations, stressing early detection, aggressive treatment, and comprehensive patient support. Continued research is crucial for enhancing disease management.
鳞状细胞癌（SCC）是一种癌性肿瘤，当正常角质形成细胞转变为侵袭性癌细胞时会发生，通常是由于影响细胞生长和分化的基因突变所致。SCC常见于皮肤暴露于阳光的部位，如面部、耳部、颈部和手部，但在脚底发生则较为罕见。
本病例是关于一名22岁男性，他因左脚底部持续疼痛前来就诊。患者提到在寻求医疗帮助前约两周脚部受过轻伤，起初是一个小伤口，但随着时间推移病情恶化。最终诊断为已扩散至肺部和淋巴结的鳞状细胞癌。
本病例强调了即使在没有已知危险因素的年轻患者中，考虑非愈合伤口发生恶性肿瘤可能性的重要性。一个简单的溃疡发展为转移性SCC的最初表现凸显了非典型表现皮肤癌诊断和管理中的挑战。
本病例突出了癌症的侵袭性和非典型的青年表现形式，强调早期检测、积极治疗和全面的患者支持。持续研究对于改善疾病管理至关重要。
