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家族性腺瘤性息肉病(FAP)患者行胰十二指肠切除术后在肝肠吻合口处出现管状腺瘤:腺瘤监测和管理的挑战。

Tubular adenoma at the hepatico-jejunal anastomosis in familial adenomatous polyposis (FAP) following pancreaticoduodenectomy: challenges in adenoma surveillance and management.

机构信息

Department of Transplantation, Beth Israel Lahey Hospital and Medical Center, Woburn, MA, USA.

Division of Gastroenterology and Hepatology, Minneapolis Veteran Affairs Medical Center, Minneapolis, MN, USA.

出版信息

Clin J Gastroenterol. 2024 Dec;17(6):1015-1018. doi: 10.1007/s12328-024-02048-0. Epub 2024 Oct 5.

Abstract

Upper gastrointestinal tumors, including ampullary adenomas, occur frequently in patients with familial adenomatous polyposis (FAP). Guidelines recommend upper gastrointestinal endoscopy in FAP for surveillance of gastric and duodenal adenomas. However, adenomas can rarely arise from biliary epithelium in patients with FAP. Here, we describe a case of tubular adenoma at the hepatico-jejunal anastomosis with intraductal extension in a patient with FAP and previous pancreaticoduodenectomy. This report illustrates a unique case and emphasizes the need for data on postoperative surveillance in patients with FAP, particularly following pancreaticoduodenectomy.

摘要

上消化道肿瘤,包括壶腹腺瘤,在家族性腺瘤性息肉病(FAP)患者中较为常见。指南建议对 FAP 患者进行上消化道内镜检查,以监测胃和十二指肠腺瘤。然而,FAP 患者的胆管上皮也可能很少发生腺瘤。本文描述了一例 FAP 患者在胰十二指肠切除术后发生肝肠吻合口管状腺瘤并伴有胆管内延伸的病例。本报告说明了一个独特的病例,并强调了 FAP 患者,特别是胰十二指肠切除术后患者的术后监测数据的重要性。

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