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胸腺切除对自发性高血压大鼠高血压发展的影响。

The effect of thymectomy on the development of hypertension in spontaneously hypertensive rats.

作者信息

Koga Y, Takeichi N, Kobayashi H

出版信息

Jpn Heart J. 1985 Sep;26(5):807-11. doi: 10.1536/ihj.26.807.

DOI:10.1536/ihj.26.807
PMID:3936945
Abstract

We studied the effect of thymectomy on the development of hypertension in spontaneously hypertensive rats (SHR). There were no significant differences between thymectomized and sham thymectomized SHR during either the initial or chronic phase of spontaneous hypertension. Similarly, administration of anti-Thyl. 1 or anti-T sera did not influence the blood pressure in SHR during the chronic phase. The results suggest that the thymus does not play a direct role in the development and maintenance of blood pressure in SHR.

摘要

我们研究了胸腺切除术对自发性高血压大鼠(SHR)高血压发展的影响。在自发性高血压的初始阶段或慢性阶段,胸腺切除的SHR与假胸腺切除的SHR之间均无显著差异。同样,在慢性阶段,给予抗Thyl. 1或抗T血清对SHR的血压也没有影响。结果表明,胸腺在SHR血压的发展和维持中不发挥直接作用。

相似文献

1
The effect of thymectomy on the development of hypertension in spontaneously hypertensive rats.胸腺切除对自发性高血压大鼠高血压发展的影响。
Jpn Heart J. 1985 Sep;26(5):807-11. doi: 10.1536/ihj.26.807.
2
The arrest of T cell maturation in spontaneously hypertensive rats with a deficient production of thymic factors.自发性高血压大鼠中胸腺因子产生不足导致T细胞成熟受阻。
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