Chen Jia-Yin, Che Xiao-Yi, Zhao Xiang-Yu, Liao Yu-Jie, Zhao Peng-Jun, Yan Fei, Fang Jue, Liu Ying, Yu Xiao-Dan, Wang Guang-Hai
Department of Developmental and Behavioral Pediatrics, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Department of Pediatric, Yangpu District Shidong Hospital, Shanghai, China.
Sleep Med. 2024 Dec;124:346-353. doi: 10.1016/j.sleep.2024.09.033. Epub 2024 Sep 29.
To examine the association between latent profiles of multi-dimensional sleep characteristics and overweight/obesity (OWO) in Chinese preschool children.
The cross-sectional analysis included 3204 preschool children recruited from 24 kindergartens in Shanghai. Parents reported children's demographics and sleep characteristics, including sleep duration, timing and disturbances. Latent profile analysis (LPA) was used to identify sleep subtypes. Logistic regression models were used to evaluate the associations between sleep characteristics/subtypes and OWO.
Short sleep duration, late bedtime, long social jetlag and sleep disturbances were significantly associated with increased OWO. However, when considering the interplay of sleep duration and timing, there was no significant association between sleep duration and OWO for children sleeping later than 22:00. Three sleep subtypes were identified based on children's sleep duration, timing and disturbances: "Average Sleepers" (n = 2107, 65.8 %), "Good Sleepers" (n = 481, 15.0 %), and "Poor Sleepers" (n = 616, 19.2 %). "Good Sleepers" had reduced odds of being OWO (AOR, 0.72; 95 % CI, 0.56-0.93) compared to "Average Sleepers", while "Poor Sleepers" showed an increased risk of OWO (AOR, 1.36; 95 % CI, 1.11-1.67).
These findings highlight that improving multiple sleep characteristics simultaneously is a promising option to prevent and intervene childhood obesity.
探讨中国学龄前儿童多维睡眠特征的潜在类别与超重/肥胖(OWO)之间的关联。
横断面分析纳入了从上海24所幼儿园招募的3204名学龄前儿童。家长报告了孩子的人口统计学信息和睡眠特征,包括睡眠时间、入睡时间和睡眠障碍。采用潜在类别分析(LPA)来识别睡眠亚型。使用逻辑回归模型评估睡眠特征/亚型与OWO之间的关联。
睡眠时间短、就寝时间晚、社交时差长和睡眠障碍与OWO增加显著相关。然而,在考虑睡眠时间和入睡时间的相互作用时,对于入睡时间晚于22:00的儿童,睡眠时间与OWO之间没有显著关联。根据儿童的睡眠时间、入睡时间和睡眠障碍确定了三种睡眠亚型:“普通睡眠者”(n = 2107,65.8%)、“良好睡眠者”(n = 481,15.0%)和“睡眠不佳者”(n = 616,19.2%)。与“普通睡眠者”相比,“良好睡眠者”患OWO的几率降低(调整后比值比[AOR],0.72;95%置信区间[CI],0.56 - 0.93),而“睡眠不佳者”患OWO的风险增加(AOR,1.36;95% CI,1.11 - 1.67)。
这些发现突出表明,同时改善多种睡眠特征是预防和干预儿童肥胖的一个有前景的选择。