School of Biomedical Engineering, Southern Medical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Guangzhou, China.
CardioCloud Medical Technology (Beijing) Co. Ltd., Beijing, China.
Artif Intell Med. 2024 Nov;157:102992. doi: 10.1016/j.artmed.2024.102992. Epub 2024 Sep 30.
Electrocardiogram (ECG) delineation is essential to the identification of abnormal cardiac status, especially when ECG signals are remotely monitored with wearable devices. The complexity and diversity of cardiac conditions generate numerous pathological ECG patterns, not only requiring the recognition of normal ECG but also addressing an extensive range of abnormal ECG patterns, posing a challenging task. Therefore, we propose an abnormal recognition-assisted network to integrate supplementary information on diverse ECG patterns. Simultaneously, we design an onset-offset aware loss to enhance precise waveform localization. Specifically, we establish a two-branch framework where ECG delineation serves as the target task, producing the final segmentation results. Additionally, the abnormal recognition-assisted network serves as an auxiliary task, extracting multi-label pathological information from ECGs. This joint learning approach establishes crucial correlations between ECG delineation and associated ECG abnormalities. The correlations enable the model to demonstrate sufficient generalization in the presence of diverse abnormal ECG patterns. Besides, onset-offset aware loss focuses intensively on wave onsets and offsets by applying biased weights to various waveform positions. This approach ensures a focus on precise localization, facilitating seamless integration into cross-entropy loss function. A large-scale wearable 12-lead dataset containing 4,913 signals is collected, offering an extensive range of ECG data for model training. Results demonstrate that our method achieves outstanding performance on two test datasets, attaining sensitivity of 94.97% and 94.27% and an error tolerance lower than 20 ms. Furthermore, our method is effective for various aberrant ECG signals, including ST-segment changes, atrial premature beats, and right and left bundle branch blocks.
心电图(ECG)的描绘对于识别异常心脏状态至关重要,特别是当心电图信号通过可穿戴设备进行远程监测时。心脏状况的复杂性和多样性产生了许多病理心电图模式,不仅需要识别正常心电图,还需要处理广泛的异常心电图模式,这是一项具有挑战性的任务。因此,我们提出了一种异常识别辅助网络,以整合关于各种心电图模式的补充信息。同时,我们设计了一个起始-结束感知损失,以增强精确的波形定位。具体来说,我们建立了一个两分支框架,其中心电图描绘作为目标任务,产生最终的分割结果。此外,异常识别辅助网络作为辅助任务,从心电图中提取多标签病理信息。这种联合学习方法在心电图描绘和相关心电图异常之间建立了重要的相关性。这些相关性使模型在存在各种异常心电图模式的情况下具有足够的泛化能力。此外,起始-结束感知损失通过对各种波形位置应用有偏差的权重,集中关注波的起始和结束。这种方法确保了精确的定位,便于无缝集成到交叉熵损失函数中。我们收集了一个包含 4913 个信号的大型可穿戴 12 导联数据集,为模型训练提供了广泛的心电图数据。结果表明,我们的方法在两个测试数据集上表现出色,达到了 94.97%和 94.27%的灵敏度,误差容忍度低于 20 毫秒。此外,我们的方法对各种异常心电图信号有效,包括 ST 段变化、房性早搏、右束支和左束支传导阻滞。