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阿富汗结核病患者的抑郁症状:一项多中心研究。

Depression symptoms among Afghan TB patients: A multi-center study.

机构信息

Department of Public Health, Faculty of Medicine, Kandahar University, Kandahar, Afghanistan.

Radiology Department, Faculty of Medicine, Kandahar University, Kandahar, Afghanistan.

出版信息

Indian J Tuberc. 2024;71 Suppl 2:S264-S268. doi: 10.1016/j.ijtb.2024.08.016. Epub 2024 Aug 29.

DOI:10.1016/j.ijtb.2024.08.016
PMID:39370194
Abstract

BACKGROUND

Depression in TB patients carries a heightened risk of treatment failure and a lower quality of life. However, no study to date has documented depression prevalence among TB patients in Afghanistan.

OBJECTIVES

We aimed to assess depression prevalence in TB patients in Southern Afghanistan.

METHODS

Between February 2023 and May 2024, a sample of 1,003 TB patients aged 18 years and above were randomly sampled in Southern Afghanistan. The questionnaire gathered patients' sociodemographic information, clinical characteristics, social support level, and the PHQ-9 (Patient Health Questionnaire). We fitted a binary logistic regression model to identify correlates of depression symptoms among TB patients.

RESULTS

Out of 1,003 patients, 69.6% (95% CI: 66.6%-72.4) had depression symptoms. We found that patients with no formal education [AOR = 3.18, 95%CI (2.35-4.30)], those with severe disease [1.84 (1.30-2.59)], patients with medical comorbidity [1.88 (1.29-2.74)], and those with low social support [1.69 (1.22-2.33)] were more likely to have depression symptoms.

CONCLUSION

TB patients in Afghanistan have high levels of depressive symptoms. Therefore, this study advocates for dedicated mental health screening and counseling services for TB patients in Afghanistan.

摘要

背景

结核病患者的抑郁会增加治疗失败的风险,并降低生活质量。然而,迄今为止,尚无研究记录阿富汗结核病患者的抑郁患病率。

目的

我们旨在评估阿富汗南部结核病患者的抑郁患病率。

方法

2023 年 2 月至 2024 年 5 月期间,我们在阿富汗南部随机抽取了 1003 名年龄在 18 岁及以上的结核病患者作为样本。问卷收集了患者的社会人口学信息、临床特征、社会支持水平和 PHQ-9(患者健康问卷)。我们拟合了二元逻辑回归模型,以确定结核病患者抑郁症状的相关因素。

结果

在 1003 名患者中,69.6%(95%置信区间:66.6%-72.4%)有抑郁症状。我们发现,未受过正规教育的患者(AOR=3.18,95%CI(2.35-4.30))、病情严重的患者(1.84(1.30-2.59))、患有合并症的患者(1.88(1.29-2.74))和社会支持度低的患者(1.69(1.22-2.33))更有可能出现抑郁症状。

结论

阿富汗的结核病患者有较高水平的抑郁症状。因此,本研究主张为阿富汗的结核病患者提供专门的心理健康筛查和咨询服务。

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