[Biosynthetic activity of cultures of different species of the genus Actinomadura].

The ability to synthesize antibiotics and exoproteases was studied in 13 species belonging to the Actinomadura genus. The antibiotic and proteolytic activities were found only in A. fulvescens INA-3321 and A. citrea INA-1849. Glycerol was shown to be the best carbon source for the growth and biosynthetic activity of A. fulvescens. A. citrea had a wider spectrum of carbon sources used for the growth and a higher proteolytic and antibiotic activity. A. citrea exerted the maximal biosynthetic activity and the best growth in a medium with starch and xylose. The effect of different nitrogen sources on the growth and biosynthetic activity of A. citrea was also studied.