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Transplant in myeloma: individualized approaches needed depending on context, access and biology.

作者信息

Vaquera-Alfaro Héctor A, Gómez-De León Andrés, Desai Nihar, Mehra Nikita, Mohyuddin Ghulam Rehman

机构信息

Hematology Service, University Hospital "Dr. José Eleuterio González" UANL, Monterrey, Nuevo León, México.

Princess Margaret Cancer Centre, Toronto, ON, Canada.

出版信息

Bone Marrow Transplant. 2025 Jan;60(1):3-5. doi: 10.1038/s41409-024-02428-7. Epub 2024 Oct 6.

DOI:10.1038/s41409-024-02428-7
PMID:39370490
Abstract
摘要

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Transplant-ineligible newly diagnosed multiple myeloma: Current and future approaches to clinical care: A Young International Society of Geriatric Oncology Review Paper.不适合移植的新诊断多发性骨髓瘤:当前和未来的临床护理方法:老年肿瘤学青年国际学会评论论文。
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Rinsho Ketsueki. 2019;60(9):1243-1256. doi: 10.11406/rinketsu.60.1243.

本文引用的文献

1
Multiple myeloma in Latin America: A systematic review.拉丁美洲的多发性骨髓瘤:一项系统综述。
EJHaem. 2024 Jun 10;5(4):867-878. doi: 10.1002/jha2.905. eCollection 2024 Aug.
2
Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.达雷妥尤单抗、硼替佐米、来那度胺和地塞米松治疗多发性骨髓瘤。
N Engl J Med. 2024 Jan 25;390(4):301-313. doi: 10.1056/NEJMoa2312054. Epub 2023 Dec 12.
3
Predictors of unsustained measurable residual disease negativity in patients with multiple myeloma.多发性骨髓瘤患者不可持续的可测量残留疾病阴性的预测因素。
Blood. 2024 Feb 15;143(7):592-596. doi: 10.1182/blood.2023022080.
4
Characteristics and outcome of infectious complications after autologous hematopoietic cell transplantation in multiple myeloma patients.多发性骨髓瘤患者自体造血细胞移植后感染并发症的特征和结果。
Transpl Infect Dis. 2023 Oct;25(5):e14123. doi: 10.1111/tid.14123. Epub 2023 Aug 12.
5
Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma.三药联合治疗、移植和维持治疗直至骨髓瘤进展。
N Engl J Med. 2022 Jul 14;387(2):132-147. doi: 10.1056/NEJMoa2204925. Epub 2022 Jun 5.
6
Impact of autologous transplantation on survival in patients with newly diagnosed multiple myeloma who have high-risk cytogenetics: A meta-analysis of randomized controlled trials.自体移植对伴有高危细胞遗传学的初诊多发性骨髓瘤患者生存的影响:一项随机对照试验的荟萃分析。
Cancer. 2022 Jun 15;128(12):2288-2297. doi: 10.1002/cncr.34211. Epub 2022 Apr 4.
7
Diagnosis and Management of Multiple Myeloma: A Review.多发性骨髓瘤的诊断与治疗:综述
JAMA. 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003.
8
Maintenance with daratumumab or observation following treatment with bortezomib, thalidomide, and dexamethasone with or without daratumumab and autologous stem-cell transplant in patients with newly diagnosed multiple myeloma (CASSIOPEIA): an open-label, randomised, phase 3 trial.在新诊断的多发性骨髓瘤患者中,硼替佐米、沙利度胺和地塞米松联合或不联合达雷妥尤单抗和自体干细胞移植治疗后,用达雷妥尤单抗或观察进行维持治疗(CASSIOPEIA):一项开放标签、随机、3 期试验。
Lancet Oncol. 2021 Oct;22(10):1378-1390. doi: 10.1016/S1470-2045(21)00428-9. Epub 2021 Sep 13.
9
Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study.自体造血干细胞移植对比硼替佐米-美法仑-泼尼松(联合或不联合硼替佐米-来那度胺-地塞米松巩固治疗)以及来那度胺维持治疗用于新诊断的多发性骨髓瘤(EMN02/HO95):一项多中心、随机、开放标签的3期研究
Lancet Haematol. 2020 Jun;7(6):e456-e468. doi: 10.1016/S2352-3026(20)30099-5. Epub 2020 Apr 30.
10
Long-Term Follow-Up Results of Lenalidomide, Bortezomib, and Dexamethasone Induction Therapy and Risk-Adapted Maintenance Approach in Newly Diagnosed Multiple Myeloma.硼替佐米、来那度胺和地塞米松诱导治疗及适应性维持治疗新诊断多发性骨髓瘤的长期随访结果。
J Clin Oncol. 2020 Jun 10;38(17):1928-1937. doi: 10.1200/JCO.19.02515. Epub 2020 Apr 16.