Merigan W H, Wood R W, Zehl D N
Neurotoxicology. 1985 Winter;6(4):81-8.
Visual thresholds, fluorescein angiography, color fundus photography and tests of motor function were used to examine the effects of carbon disulfide (CS2) on macaque monkeys. After reliable baseline measures were obtained, two monkeys were exposed to 256 ppm CS2, 6 hours a day, 5 days each week for 7 weeks. A third monkey was tested similarly but received a sham exposure over the same period. Visual acuity of the exposed monkeys dropped more than 5 fold during exposure and showed a partial subsequent recovery only in one monkey. Flicker resolution, on the other hand, was only slightly and transiently impaired. Tests of motor function also showed only brief and partial disruption. No evidence was seen in either exposed monkey of the retinal vascular changes that are currently the major diagnostic signs in human carbon disulfide poisoning.
使用视觉阈值、荧光素血管造影、彩色眼底照相和运动功能测试来检查二硫化碳（CS2）对猕猴的影响。在获得可靠的基线测量值后，两只猴子每天暴露于256 ppm的CS2中，每周6小时，共7周。第三只猴子接受了类似测试，但在同一时期接受了假暴露。暴露猴子的视力在暴露期间下降了5倍以上，只有一只猴子随后出现了部分恢复。另一方面，闪烁分辨率仅受到轻微和短暂的损害。运动功能测试也仅显示出短暂和部分的破坏。在任何一只暴露的猴子中，均未发现目前人类二硫化碳中毒主要诊断体征的视网膜血管变化迹象。
