Mazhari Mohammad Yusuf Ali, Agnihotry Anukriti, Priyadarshi Mayank, Chaurasia Suman, Singh Poonam, Basu Sriparna
Senior Resident, Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Junior Resident, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Trop Doct. 2025 Jan;55(1):67-68. doi: 10.1177/00494755241287809. Epub 2024 Oct 7.
There is a high risk of severe varicella infection in the neonate when the mother develops a rash around the time of delivery. Current guidelines recommend separation of mother-baby dyad and passive immunization to prevent severe infection in such cases. We report a case of severe varicella in a neonate whose mother developed primary varicella infection two days prior to delivery. The neonate had a fatal outcome despite physical separation from mother and passive immunization in the immediate postnatal period.
当母亲在分娩前后出现皮疹时，新生儿有发生严重水痘感染的高风险。当前指南建议母婴分离并进行被动免疫，以预防此类情况下的严重感染。我们报告一例新生儿严重水痘病例，其母亲在分娩前两天发生原发性水痘感染。尽管新生儿在出生后立即与母亲进行了物理隔离并接受了被动免疫，仍出现了致命结局。
