运动诱发哮喘儿童鼻阻力的变化

Exercise-induced change of nasal resistance in asthmatic children.

作者信息

Hasegawa M, Kabasawa Y, Ohki M, Watanabe I

出版信息

Otolaryngol Head Neck Surg. 1985 Dec;93(6):772-6. doi: 10.1177/019459988509300614.

DOI:10.1177/019459988509300614

Abstract

Exercise-induced change of nasal resistance and forced expiratory volume in 1 second (FEV1.0) were studied in 30 asthmatic children and seven normal children. Exercise-induced asthma (EIA) was diagnosed in 19 (63%) of the 30 asthmatic patients. Unilateral complete nasal blockage after exercise (exercise-induced nasal obstruction [EINO]) was found in nine (30%) of the 30 asthmatic patients. A marked decrease in nasal resistance took place immediately or 4 minutes after exercise in all cases. EIA is most severe 5 minutes after exercise, and EINO took place 14 or 19 minutes after exercise. The seven normal children had neither EIA nor EINO. The pathophysiologic relationship between EIA and EINO is discussed.

摘要

对30名哮喘儿童和7名正常儿童进行了运动诱导的鼻阻力变化和一秒用力呼气量（FEV1.0）的研究。30名哮喘患者中有19名（63%）被诊断为运动诱发性哮喘（EIA）。30名哮喘患者中有9名（30%）在运动后出现单侧完全性鼻阻塞（运动诱发性鼻阻塞[EINO]）。所有病例在运动后即刻或4分钟时鼻阻力均显著下降。EIA在运动后5分钟最为严重，而EINO在运动后14或19分钟出现。7名正常儿童既没有EIA也没有EINO。本文讨论了EIA与EINO之间的病理生理关系。