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中风:急性缺血性中风新型治疗方式的进展

Stroke: Evolution of newer treatment modalities for acute ischemic stroke.

作者信息

Nag Deb Sanjay, Swain Amlan, Sahu Seelora, Sen Biswajit, Parween Sadiya

机构信息

Department of Anaesthesiology, Tata Main Hospital, Jamshedpur 831001,

Department of Anaesthesiology, Tata Main Hospital, Jamshedpur 831001, India.

出版信息

World J Clin Cases. 2024 Oct 6;12(28):6137-6147. doi: 10.12998/wjcc.v12.i28.6137.

DOI:10.12998/wjcc.v12.i28.6137
PMID:39371560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11362888/
Abstract

Acute ischemic stroke is one of the leading causes of morbidity and mortality worldwide. Restoration of cerebral blood flow to affected ischemic areas has been the cornerstone of therapy for patients for eligible patients as early diagnosis and treatment have shown improved outcomes. However, there has been a paradigm shift in the management approach over the last decade, and with the emphasis currently directed toward including newer modalities such as neuroprotection, stem cell treatment, magnetic stimulation, anti-apoptotic drugs, delayed recanalization, and utilization of artificial intelligence for early diagnosis and suggesting algorithm-based management protocols.

摘要

急性缺血性中风是全球发病和死亡的主要原因之一。恢复受影响缺血区域的脑血流一直是符合条件患者治疗的基石,因为早期诊断和治疗已显示出更好的结果。然而,在过去十年中,管理方法发生了范式转变,目前重点转向纳入更新的治疗方式,如神经保护、干细胞治疗、磁刺激、抗凋亡药物、延迟再通,以及利用人工智能进行早期诊断并提出基于算法的管理方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d115/11362888/2b73158ff49c/WJCC-12-6137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d115/11362888/2b73158ff49c/WJCC-12-6137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d115/11362888/2b73158ff49c/WJCC-12-6137-g001.jpg

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World J Clin Cases. 2024 Feb 6;12(4):677-680. doi: 10.12998/wjcc.v12.i4.677.
2
2023 Neurocritical Care Updates in Cerebrovascular Disease.2023年脑血管疾病的神经重症监护最新进展
Stroke. 2023 Oct;54(10):2671-2675. doi: 10.1161/STROKEAHA.123.043018. Epub 2023 Sep 25.
3
Artificial Intelligence and the Evaluation and Treatment of Stroke.人工智能与中风的评估和治疗
Dela J Public Health. 2023 Aug 31;9(3):82-84. doi: 10.32481/djph.2023.08.014. eCollection 2023 Aug.
4
Nanotechnology in Stroke: New Trails with Smaller Scales.纳米技术在中风治疗中的应用:更小尺度的新路径。
Biomedicines. 2023 Mar 4;11(3):780. doi: 10.3390/biomedicines11030780.
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Acute ischaemic stroke: recent advances in reperfusion treatment.急性缺血性脑卒中:再灌注治疗的新进展。
Eur Heart J. 2023 Apr 7;44(14):1205-1215. doi: 10.1093/eurheartj/ehac684.
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Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities.以年龄或动脉粥样硬化作为合并症的卒中啮齿动物模型中芬戈莫德的临床前评估
Front Pharmacol. 2022 Jul 13;13:920449. doi: 10.3389/fphar.2022.920449. eCollection 2022.
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