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New frontiers in radioembolization.

作者信息

Mansur Arian, Habibollahi Peiman, Fang Adam, Mahvash Armeen, Etezadi Vahid, Liddell Robert P, Camacho Juan C, Cohen Emil I, Kokabi Nima, Arepally Aravind, Georgiades Christos, Nezami Nariman

机构信息

Harvard Medical School, Boston, MA, USA.

Division of Diagnostic Imaging, Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Ther Adv Med Oncol. 2024 Sep 30;16:17588359241280692. doi: 10.1177/17588359241280692. eCollection 2024.

DOI:10.1177/17588359241280692
PMID:39371617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456171/
Abstract

Radioembolization is a locoregional transarterial therapy that combines radionuclide and micron-sized beads to deliver radiation internally to the target tumors based on the arterial blood flow. While initially developed as a palliative treatment option, radioembolization is now used for curative intent treatment, neoadjuvant therapy, and method to downstage or bridge for liver transplant. Radioembolization has become increasingly utilized and is an important therapeutic option for the management of hepatocellular carcinoma and liver metastasis. This article provides an overview of the techniques, challenges, and novel developments in radioembolization, including new dosimetry techniques, radionuclides, and new target tumors.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/8e79bdf9e27c/10.1177_17588359241280692-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/6a89efed514e/10.1177_17588359241280692-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/57061315375e/10.1177_17588359241280692-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/d6f703d5d2bf/10.1177_17588359241280692-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/94a3ce22e51f/10.1177_17588359241280692-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/8e79bdf9e27c/10.1177_17588359241280692-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/6a89efed514e/10.1177_17588359241280692-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/57061315375e/10.1177_17588359241280692-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/d6f703d5d2bf/10.1177_17588359241280692-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/94a3ce22e51f/10.1177_17588359241280692-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cea/11456171/8e79bdf9e27c/10.1177_17588359241280692-fig5.jpg

相似文献

[1]
New frontiers in radioembolization.

Ther Adv Med Oncol. 2024-9-30

[2]
Evolution of Radioembolization in Treatment of Hepatocellular Carcinoma: A Pictorial Review.

Radiographics. 2021-10

[3]
Patient Selection and Clinical Outcomes of Y90 in Hepatocellular Carcinoma.

Tech Vasc Interv Radiol. 2019-6

[4]
Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports.

Einstein (Sao Paulo). 2020-2-27

[5]
Transarterial Radioembolization for Management of Hepatocellular Carcinoma.

Oncologist. 2024-2-2

[6]
Radioembolization for primary and metastatic liver cancer.

Semin Radiat Oncol. 2011-10

[7]
Radioembolization of HCC and secondary hepatic tumors: a comprehensive review.

Q J Nucl Med Mol Imaging. 2024-12

[8]
Evolution of Personalized Dosimetry for Radioembolization of Hepatocellular Carcinoma.

J Vasc Interv Radiol. 2023-7

[9]
Selective internal radiation therapy segmentectomy: A new minimally invasive curative option for primary liver malignancies?

World J Gastroenterol. 2024-5-14

[10]
Local Arterial Therapies in the Management of Unresectable Hepatocellular Carcinoma.

Curr Treat Options Oncol. 2017-10-27

引用本文的文献

[1]
Spatial distribution of fractionally administered holmium microspheres in non-tumorous human liver tissue: how livers survive transarterial radioembolisation.

EJNMMI Res. 2025-4-28

[2]
Expanding the Scope of Interventional Oncology: Locoregional Therapies in Extrahepatic Malignancies.

Cancers (Basel). 2025-2-21

本文引用的文献

[1]
Radioembolization plus Immune Checkpoint Inhibitor Therapy Compared with Radioembolization plus Tyrosine Kinase Inhibitor Therapy for the Treatment of Hepatocellular Carcinoma.

J Vasc Interv Radiol. 2024-5

[2]
A Pilot Study of Pembrolizumab in Combination With Y90 Radioembolization in Subjects With Poor Prognosis Hepatocellular Carcinoma.

Oncologist. 2024-3-4

[3]
Ablation versus Radiation Segmentectomy for Small Liver Tumors.

Semin Intervent Radiol. 2024-1-24

[4]
Safety and Efficacy of Concurrent Atezolizumab/Bevacizumab or Nivolumab Combination Therapy with Yttrium-90 Radioembolization of Advanced Unresectable Hepatocellular Carcinoma.

Curr Oncol. 2023-11-25

[5]
AAPM Medical Physics Practice Guideline 14.a: Yttrium-90 microsphere radioembolization.

J Appl Clin Med Phys. 2024-2

[6]
Chemotherapy with or without selective internal radiation therapy for intrahepatic cholangiocarcinoma: Data from clinical trials.

Hepatology. 2024-1-1

[7]
A Phase I/IIa Trial of Yttrium-90 Radioembolization in Combination with Durvalumab for Locally Advanced Unresectable Hepatocellular Carcinoma.

Clin Cancer Res. 2023-9-15

[8]
Neuroendocrine liver metastases treated using transarterial radioembolization: Identification of prognostic parameters at 68Ga-DOTATATE PET/CT.

Diagn Interv Imaging. 2024-1

[9]
Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: An early exploratory analysis of real-world data.

Liver Int. 2023-8

[10]
Joint EANM/SNMMI/IHPBA procedure guideline for [Tc]Tc-mebrofenin hepatobiliary scintigraphy SPECT/CT in the quantitative assessment of the future liver remnant function.

HPB (Oxford). 2023-10

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