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酷似原位胃腺癌的孤立性原发性胃浆细胞瘤

Solitary Giant Primary Gastric Plasmacytoma Mimicking Gastric Adenocarcinoma In Situ.

作者信息

Bolivar Sergio A, Medina Patricia, Fuentes Maria Cynthia, Martinez-Cordero Humberto, Salguedo German

机构信息

Internal Medicine, Hospital Militar Central, Bogotá, COL.

Hematology, Hospital Militar Central, Bogotá, COL.

出版信息

Cureus. 2024 Sep 4;16(9):e68674. doi: 10.7759/cureus.68674. eCollection 2024 Sep.

DOI:10.7759/cureus.68674
PMID:39371703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11452553/
Abstract

A solitary extraosseous plasmacytoma is a rare type of plasma cell neoplasm. Its occurrence in the stomach is particularly unusual and can easily be mistaken for more common types of tumors. We describe a case involving a solitary extraosseous plasmacytoma in a patient who experienced weight loss as the sole symptom. Initially, the condition was misdiagnosed as gastric adenocarcinoma based on endoscopic biopsy results, leading to a gastrectomy after neoadjuvant chemotherapy. Subsequent examination of the pathological specimen revealed the presence of plasma cell neoplasia alongside a gastric adenocarcinoma in situ.

摘要

孤立性骨外浆细胞瘤是一种罕见的浆细胞肿瘤类型。它发生在胃部尤其不寻常，很容易被误诊为更常见的肿瘤类型。我们描述了一例涉及一名患者的孤立性骨外浆细胞瘤病例，该患者仅以体重减轻为唯一症状。最初，根据内镜活检结果，该病症被误诊为胃腺癌，在新辅助化疗后进行了胃切除术。随后对病理标本的检查显示，除原位胃腺癌外还存在浆细胞瘤形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/11452553/eb2177881f57/cureus-0016-00000068674-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/11452553/42ce8d2cda28/cureus-0016-00000068674-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/11452553/eb2177881f57/cureus-0016-00000068674-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/11452553/42ce8d2cda28/cureus-0016-00000068674-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/11452553/eb2177881f57/cureus-0016-00000068674-i02.jpg

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本文引用的文献

1
Plasma cell neoplasms and related entities-evolution in diagnosis and classification.浆细胞肿瘤及相关疾病——诊断和分类的演变。
Virchows Arch. 2023 Jan;482(1):163-177. doi: 10.1007/s00428-022-03431-3. Epub 2022 Nov 21.
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Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts-A follow-up.髓外浆细胞瘤：肿瘤发生和治疗概念——随访。
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Case report: gastric plasmacytoma resistant to radiation therapy.病例报告：对放射治疗有抵抗性的胃浆细胞瘤。
Postgrad Med. 2022 Jan;134(1):122-123. doi: 10.1080/00325481.2021.2008726. Epub 2021 Nov 29.
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Gastrointestinal manifestations of extramedullary plasmacytoma: a narrative review and illustrative case reports.髓外浆细胞瘤的胃肠道表现：一项叙述性综述及病例报告
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Int J Surg Case Rep. 2016;27:133-136. doi: 10.1016/j.ijscr.2016.08.041. Epub 2016 Sep 3.
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Successful treatment of a gastric plasmacytoma using a combination of endoscopic submucosal dissection and oral thalidomide.采用内镜下黏膜下剥离术联合口服沙利度胺成功治疗胃浆细胞瘤。
Clin Endosc. 2014 Nov;47(6):564-7. doi: 10.5946/ce.2014.47.6.564. Epub 2014 Nov 30.
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Imaging findings of primary gastric plasmacytoma: a case report.原发性胃浆细胞瘤的影像学表现：一例报告
World J Gastroenterol. 2014 Aug 7;20(29):10202-7. doi: 10.3748/wjg.v20.i29.10202.
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Discovery of a rare ileocecal plasmacytoma.罕见回盲部浆细胞瘤的发现。
J Surg Case Rep. 2014 Mar 30;2014(3):rju016. doi: 10.1093/jscr/rju016.
10
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Korean J Gastroenterol. 2014 May;63(5):316-20. doi: 10.4166/kjg.2014.63.5.316.