Clayton Hannah, Miller Mark
General Surgery, DeBusk College of Osteopathic Medicine, Lincoln Memorial University, Memphis, USA.
General Surgery, Methodist Le Bonheur Germantown Hospital, Memphis, USA.
Cureus. 2024 Sep 4;16(9):e68665. doi: 10.7759/cureus.68665. eCollection 2024 Sep.
Tuberculosis (TB) peritonitis resulting in a small bowel obstruction is uncommon and can be a challenging infectious disease to diagnose. It often has an insidious onset with non-specific symptoms. Today we report a rare case of a 30-year-old woman who recently traveled to Vietnam and presented with worsening upper and lower gastrointestinal symptoms. CT scan revealed an ill-defined mass in the terminal ileum with prominent mucosal enhancement and wall thickening, which ultimately led to subsequent colonoscopy and Quantiferon Gold testing, revealing a positive result. Biopsy of the mass demonstrated noncaseating granulomatous colitis with rare acid-fast positive bacillus consistent with mycobacterial infection. As a result, the patient was ultimately initiated on antituberculosis therapy. Shortly thereafter, she was readmitted with clinical features suggestive of a bowel obstruction. The patient was managed with supportive care and did not require surgical intervention. However, approximately two months following the readmission, she presented to the emergency department once again with a mechanical bowel obstruction that ultimately required surgery. This case underscores the importance of TB testing in patients with insidious, worsening gastrointestinal symptoms and highlights the potential complications of TB peritonitis, even in those undergoing antituberculosis treatment.
结核性腹膜炎导致小肠梗阻并不常见,是一种诊断颇具挑战性的传染病。其发病往往隐匿,症状不具特异性。今日我们报告一例罕见病例,一名30岁女性近期前往越南,出现上、下消化道症状加重。CT扫描显示回肠末端有一界限不清的肿块,黏膜强化显著且肠壁增厚,最终促使后续进行结肠镜检查及结核菌素金标检测,结果呈阳性。肿块活检显示为非干酪样肉芽肿性结肠炎,罕见抗酸阳性杆菌,符合分枝杆菌感染。因此,患者最终开始接受抗结核治疗。此后不久,她因提示肠梗阻的临床症状再次入院。患者接受了支持治疗,无需手术干预。然而,再次入院约两个月后,她再次前往急诊科,出现机械性肠梗阻,最终需要手术治疗。该病例强调了对隐匿性、进行性加重的胃肠道症状患者进行结核检测的重要性,并突出了结核性腹膜炎的潜在并发症,即使是在接受抗结核治疗的患者中。