Niamita Laili Fitri, Daviq Mochammad, Rusli Musofa, Arifijanto Muhammad Vitanata
Study Program of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Division of Tropical Disease and Infection, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Hospital Surabaya, Indonesia.
Int J Surg Case Rep. 2024 Aug;121:109977. doi: 10.1016/j.ijscr.2024.109977. Epub 2024 Jun 29.
Diagnosing peritoneal tuberculosis is challenging due to unspecific clinical manifestations, particularly in immunocompromised patients with HIV/AIDS and tuberculosis infections.
An Indonesian man, 26-years-old, complained of mid-abdominal colic and constipation. The patient's present state exhibited symptoms of weakness and paleness, oral candidiasis, a bloated abdomen, palpable discomfort, and shifting dullness. The ascitic fluid analysis showed increased ADA (709 U/L), and detected Mycobacterium tuberculosis using GeneXpert MTB/RIF. Radiographic examination from abdominal x-ray and CT scan revealed a small bowel obstruction. He received intestinal decompression, pain control, intravenous fluid resuscitation, and correction of electrolyte imbalance for small bowel obstruction without any indication for surgical intervention. He also receive first-line ATD for 2 months during intensive phase and 4 months for continuous phase. After a period of 2 weeks following the ATD administration, the patient began taking ARV medication on a daily basis. He showed a good prognosis 6 months following.
The diagnosis of peritoneal tuberculosis is challenging due to its unspecific manifestation and some cases are identified when complications such as small bowel obstruction appear. The ADA test and GenExpert MTB/RIF are useful instruments for promptly diagnosing tuberculosis. It is suggested to use ARV treatment in individuals with HIV/AIDS who have peritoneal tuberculosis, starting 2 weeks following ATD treatments.
Peritoneal tuberculosis with small bowel obstruction and HIV/AIDS infection is a rare case in which early diagnosis and monitoring play an important role in successful treatment.
由于临床表现不具特异性,诊断腹膜结核具有挑战性,尤其是在合并人类免疫缺陷病毒/获得性免疫综合征(HIV/AIDS)和结核感染的免疫功能低下患者中。
一名26岁的印度尼西亚男子,主诉中腹部绞痛和便秘。患者目前状态表现为虚弱、面色苍白、口腔念珠菌病、腹部膨隆、可触及不适及移动性浊音。腹水分析显示腺苷脱氨酶(ADA)升高(709 U/L),并使用GeneXpert MTB/RIF检测到结核分枝杆菌。腹部X线和CT扫描的影像学检查显示小肠梗阻。他接受了小肠梗阻的肠道减压、疼痛控制、静脉补液复苏及电解质失衡纠正,无手术干预指征。他还在强化期接受了2个月的一线抗结核药物治疗,持续期接受了4个月的治疗。在给予抗结核药物治疗2周后,患者开始每日服用抗逆转录病毒药物。6个月后他显示出良好的预后。
由于腹膜结核的表现不具特异性,其诊断具有挑战性,一些病例在出现小肠梗阻等并发症时才得以确诊。ADA检测和GeneXpert MTB/RIF是快速诊断结核病的有用工具。建议在患有腹膜结核的HIV/AIDS个体中,在抗结核药物治疗2周后开始使用抗逆转录病毒治疗。
伴有小肠梗阻和HIV/AIDS感染的腹膜结核是一种罕见病例,早期诊断和监测对成功治疗起着重要作用。