Patil Abhishek, Durai Prem, Shetti Preeti, Desai Teena, Teli Suprita
Neurosurgery, Jawaharlal Nehru Medical College, Belgaum, IND.
Otolaryngology - Head and Neck Surgery, Jawaharlal Nehru Medical College, Belgaum, IND.
Cureus. 2024 Sep 5;16(9):e68687. doi: 10.7759/cureus.68687. eCollection 2024 Sep.
Sinonasal cancers are rare tumors with squamous cell carcinoma (SCC) being one of the more common histological subtypes. These carcinomas typically invade the sinus cavity from which they originate, progressively eroding surrounding bony structures and extending to adjacent anatomical regions. In rare instances, they may breach the posterior or superior walls to invade the anterior cranial fossa (ACF) and frontal lobes. The normal flora of the nasal cavity and paranasal sinuses includes , , α- and γ-streptococci, , and aerobic diphtheroids. To our knowledge, cases of sinonasal malignancies extending into the frontal sinus and ACF, leading to a frontal lobe abscess caused by these organisms, have not been well-documented. We present a case of a 36-year-old male who underwent surgery for a right frontal brain abscess caused by . Histopathological analysis of the abscess wall revealed moderately differentiated SCC arising from the paranasal sinuses, highlighting a rare and intriguing presentation of this disease.
鼻窦癌是罕见肿瘤,其中鳞状细胞癌(SCC)是较常见的组织学亚型之一。这些癌通常从其起源的鼻窦腔侵入,逐渐侵蚀周围的骨结构并延伸至相邻的解剖区域。在罕见情况下,它们可能会突破后壁或上壁以侵入前颅窝(ACF)和额叶。鼻腔和鼻窦的正常菌群包括 、 、α和γ链球菌、 以及需氧类白喉杆菌。据我们所知,鼻窦恶性肿瘤延伸至额窦和ACF并导致由这些微生物引起的额叶脓肿的病例尚未得到充分记录。我们报告一例36岁男性因 导致的右额叶脑脓肿接受手术的病例。脓肿壁的组织病理学分析显示鼻窦发生中度分化的SCC,突出了这种疾病罕见且有趣的表现。