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咪达唑仑作为全身麻醉下小儿牙科患者麻醉前用药的口服与鼻内给药的比较评价

Comparative Evaluation of Oral and Intranasal Administration of Midazolam as Preanesthetic Medication in Pediatric Dental Patients Treated under General Anesthesia.

作者信息

Shah Ruby K, Tandon Sandeep, Mathur Rinku, Sharma Tripti, Rathor Ambika S

机构信息

Department of Dentistry, RUHS College of Medical Sciences, Jaipur, Rajasthan, India.

Department of Dentistry, Mediclinic Airport Road Hospital, Abu Dhabi, United Arab Emirates.

出版信息

Int J Clin Pediatr Dent. 2024 Aug;17(8):881-886. doi: 10.5005/jp-journals-10005-2941.

DOI:10.5005/jp-journals-10005-2941
PMID:39372344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11451862/
Abstract

AIMS AND BACKGROUND

Midazolam is commonly used as a preanesthetic medication for behavior management of children. The current study is conducted to find out the effect of midazolam through nasal and oral routes as a premedicament in pediatric patients treated under general anesthesia. The main aims of the study were: to compare the effect of oral syrup and intranasal spray as preanesthetic medication; to record the undesirable side effects of midazolam by both routes.

MATERIALS AND METHODS

The patients aged 2-6 years of either sex were randomly divided into two equal groups of 30 each-group I: oral; group II: intranasal.

RESULTS

The oral and intranasal routes of midazolam were found to be equally effective and provided adequate sedation for easy separation from the parents and cooperation from children during the induction of anesthesia with minimal side effects.

CONCLUSION

Based on the study results, we can conclude that both oral and intranasal midazolam can be used as preanesthetic medication for pediatric dental patients treated under general anesthesia.

CLINICAL SIGNIFICANCE

In pediatric patients, the oral route should be preferred for midazolam premedication in comparison to the intranasal route.

HOW TO CITE THIS ARTICLE

Swati, Shah RK, Tandon S, . Comparative Evaluation of Oral and Intranasal Administration of Midazolam as Preanesthetic Medication in Pediatric Dental Patients Treated under General Anesthesia. Int J Clin Pediatr Dent 2024;17(8):881-886.

摘要

目的与背景

咪达唑仑常用于儿童行为管理的麻醉前用药。本研究旨在探究咪达唑仑经鼻和经口途径作为全身麻醉下儿科患者术前用药的效果。该研究的主要目的为：比较口服糖浆和鼻内喷雾作为麻醉前用药的效果；记录两种途径使用咪达唑仑的不良副作用。

材料与方法

将年龄在2至6岁的男女患者随机分为两组，每组30人——第一组：口服；第二组：鼻内给药。

结果

发现咪达唑仑经口和经鼻途径同样有效，且在麻醉诱导期间能提供足够的镇静效果，便于患儿与父母分离并获得患儿的配合，副作用最小。

结论

基于研究结果，我们可以得出结论，口服和鼻内使用咪达唑仑均可作为全身麻醉下儿科牙科患者的麻醉前用药。

临床意义

在儿科患者中，与鼻内途径相比，咪达唑仑术前用药应首选口服途径。

如何引用本文

斯瓦蒂、沙阿·RK、坦登·S等。全身麻醉下儿科牙科患者口服和鼻内给予咪达唑仑作为麻醉前用药的比较评估。《国际临床儿科牙科学杂志》2024年；17(8)：881 - 886。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/9dcf22fafff2/ijcpd-17-881-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/4c1f0612f37c/ijcpd-17-881-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/ef64261b10ed/ijcpd-17-881-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/9dcf22fafff2/ijcpd-17-881-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/4c1f0612f37c/ijcpd-17-881-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/ef64261b10ed/ijcpd-17-881-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c49/11451862/9dcf22fafff2/ijcpd-17-881-g003.jpg

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Comparison of oral ketamine and oral midazolam as sedative agents in pediatric dentistry.口服氯胺酮与口服咪达唑仑作为儿科牙科镇静剂的比较。
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