1例因抗精神病药恶性综合征引发的肌红蛋白管型肾病
A Case of Neuroleptic Malignant Syndrome-Prompted Myoglobin Cast Nephropathy.
作者信息
Patel Prem S, Singh Prit P, Kumar Om
机构信息
Department of Nephrology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India.
Department of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
出版信息
Indian J Nephrol. 2024 Sep-Oct;34(5):524-526. doi: 10.4103/ijn.ijn_137_23. Epub 2023 Jun 5.
Myoglobin cast nephropathy is a sequel of rhabdomyolysis, and is characterized by the release of free myoglobin in the circulation, direct proximal convoluted tubule injury, and obstruction by myoglobin cast in distal tubules. We report an interesting case of myoglobin cast nephropathy in a patient who was on neuroleptic drugs and who presented with neuroleptic malignant syndrome and acute kidney injury.
肌红蛋白管型肾病是横纹肌溶解症的后遗症，其特征为循环中游离肌红蛋白的释放、近端肾小管的直接损伤以及远端肾小管中肌红蛋白管型的阻塞。我们报告了一例有趣的肌红蛋白管型肾病病例，该患者正在服用抗精神病药物，并出现了抗精神病药物恶性综合征和急性肾损伤。
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