Jura W G, Brown C G, Perry M
Vet Parasitol. 1985 Dec;18(4):339-48. doi: 10.1016/0304-4017(85)90068-8.
Cyclical interactions between intracellular schizonts of the Ankara and Hissar strains of Theileria annulata and the Muguga strain of T. parva and the parasitised host lymphoblasts have been studied autoradiographically by following the incorporation of (3H) thymidine into parasite and host cell nuclei, and also by quantitating the number of schizont nuclei per lymphoblast, at various stages and phases of host cell cycle. The synthesis of DNA by Theileria schizonts and the parasitised host lymphoblasts was found to be asynchronous and to occur at different phases of the host cell interphase stage. While the lymphoblast nuclear DNA incorporates (3H) thymidine during the S phase, schizont nuclei were labelled during the G2 phase of the host lymphoblast interphase stage. The replication of schizont nuclei took place before the metaphase stage of host cell cycle, viz, prometaphase, so that the mean schizont nuclear number at host prometaphase and at anaphase--telophase was consistently more or less double the mean nuclear number at interphase.
通过追踪（3H）胸腺嘧啶核苷掺入寄生虫和宿主细胞核的情况，并在宿主细胞周期的不同阶段和时期对每个淋巴母细胞内裂殖体细胞核的数量进行定量，利用放射自显影术研究了环形泰勒虫安卡拉株和希萨尔株以及微小泰勒虫穆古加株的细胞内裂殖体与被寄生的宿主淋巴母细胞之间的周期性相互作用。发现泰勒虫裂殖体和被寄生的宿主淋巴母细胞的DNA合成是不同步的，且发生在宿主细胞间期的不同阶段。当淋巴母细胞核DNA在S期掺入（3H）胸腺嘧啶核苷时，裂殖体细胞核在宿主淋巴母细胞间期的G2期被标记。裂殖体细胞核的复制发生在宿主细胞周期的中期之前，即前中期，因此宿主前中期和后期 - 末期的平均裂殖体细胞核数量始终或多或少是间期平均核数量的两倍。
