Skinner Janelle A, Leary Mark, Wynne Olivia, Hay Phillipa J, Collins Clare E, Burrows Tracy L
School of Health Sciences, College of Health, Medicine and Wellbeing, University of Newcastle, University Drive, Callaghan NSW 2308, Australia.
Hunter Medical Research Institute, University of Newcastle, Lot 1 Kookaburra Cct, New Lambton Heights, NSW 2305, Australia.
J Public Health (Oxf). 2024 Dec 1;46(4):564-574. doi: 10.1093/pubmed/fdae273.
The TRACE (Targeted Research for Addictive and Compulsive Eating) intervention was evaluated in a 3-month randomized controlled trial which demonstrated significant improvement in Yale Food Addiction Scale scores favoring dietitian-led telehealth (active intervention) compared with passive and control groups. This study aimed to determine intervention costs and cost-utility.
Costs of each intervention (2021$AUD) and incremental net monetary benefit (iNMB; incremental benefit, defined as Quality-Adjusted Life Years (QALY) gained, multiplied by willingness to pay threshold minus incremental cost) were calculated to estimate differences between groups.
The active intervention (n = 38) cost $294 (95% UI: $266, $316) per person compared to $47 (95% UI: $40, $54) in the passive intervention (n = 24), and $26 in the control group (n = 37). At a cost-effectiveness threshold of $50 000 per QALY score gained, the active intervention iNMB was -$186 (95% UI: -$1137, $834) and the passive group $127 (95% UI: -$1137, $834). Compared to the control group, estimates indicate a 30% chance of the active intervention, and a 60% chance of the passive intervention being cost effective.
Although the overall cost of the active intervention was low, this was not considered cost-effective in comparison to the passive intervention, given small QALY score gains.
Australia New Zealand Clinical Trial Registry ACTRN12621001079831.
在一项为期3个月的随机对照试验中对TRACE（成瘾性和强迫性饮食的靶向研究）干预措施进行了评估，结果表明，与被动组和对照组相比，由营养师主导的远程医疗（积极干预）在耶鲁食物成瘾量表评分方面有显著改善。本研究旨在确定干预成本和成本效益。
计算每种干预措施的成本（2021澳元）和增量净货币效益（iNMB；增量效益，定义为获得的质量调整生命年（QALY）乘以支付意愿阈值减去增量成本），以估计组间差异。
积极干预组（n = 38）每人成本为294澳元（95% UI：266澳元，316澳元），被动干预组（n = 24）为47澳元（95% UI：40澳元，54澳元），对照组（n = 37）为26澳元。在每获得一个QALY评分为50000澳元的成本效益阈值下，积极干预组的iNMB为 - 186澳元（95% UI： - 1137澳元，834澳元），被动组为127澳元（95% UI： - 1137澳元，834澳元）。与对照组相比，估计积极干预措施有30%的可能性具有成本效益，被动干预措施有60%的可能性具有成本效益。
尽管积极干预措施的总体成本较低，但鉴于获得的QALY评分较小，与被动干预措施相比，这被认为不具有成本效益。
澳大利亚新西兰临床试验注册中心ACTRN12621001079831。
