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[Prognostic factors and results of external irradiation of cancers of the base of the tongue].

作者信息

Jaulerry C, Bataini J P, Brunin F, Rodriguez J, Brugère J

出版信息

Ann Otolaryngol Chir Cervicofac. 1985;102(7):519-24.

PMID:3937474
Abstract

At the Curie Institute, between 1958-1980, 166 patients were treated for squamous cell carcinoma of the base of the tongue, by external radiotherapy alone. The absolute survival was 45%, 39%, 26% at 2, 3, 5 years. 95% local and loco-regional failures arrived within the first two years; the nodal failures isolated were rare (4%). Unfavorable prognosis features are: the size of the tumor and the clinical radiation-induced regression of the primary. A new therapeutic approach is discussed: an additive curietherapy for some T1-T2 and a surgical excision (total glossectomy with or without neck dissection) for some T3-T4 of which the regression is unsatisfactory at 50-55 Gy are proposed.

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