Jaulerry C, Brunin F, Rodriguez J, Bataïni J P, Brugère J
Ann Otolaryngol Chir Cervicofac. 1986;103(8):559-63.
Between 1960 to 1982, 98 patients with squamous cell carcinomas of the posterior pharyngeal wall were treated at the Curie Institute by radiotherapy alone. The absolute survival is 30% and 18% at three and five years. The major cause of death is loco-regional failure. 95% of the local failures arrived within the 18 first months. The 2 years control rate ranged from 80% for T1, 64% for T2, to 36% for T3 and 22% for T4. The local control is so depending on the radiation induced regression of the primary. The 2 years control rate is 71% for the patients with complete regression and 12% for the patients with not complete regression at the end of the treatment. The improvement of these results by adjunction of other treatments (surgery, chemotherapy, hyperthermia) is discussed.
1960年至1982年间,居里研究所仅采用放射疗法治疗了98例下咽后壁鳞状细胞癌患者。三年和五年的绝对生存率分别为30%和18%。主要死亡原因是局部区域复发。95%的局部复发发生在最初的18个月内。两年控制率从T1期的80%、T2期的64%,到T3期的36%和T4期的22%不等。局部控制情况取决于原发灶放疗后的退缩情况。治疗结束时,完全退缩患者的两年控制率为71%,未完全退缩患者的两年控制率为12%。文中还讨论了通过联合其他治疗方法(手术、化疗、热疗)改善这些结果的情况。