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[下咽后壁癌。居里研究所的经验。放射治疗结果分析]

[Carcinomas of the posterior pharyngeal wall. Experience of the Institut Curie. Analysis of the results of radiotherapy].

作者信息

Jaulerry C, Brunin F, Rodriguez J, Bataïni J P, Brugère J

出版信息

Ann Otolaryngol Chir Cervicofac. 1986;103(8):559-63.

PMID:3827078
Abstract

Between 1960 to 1982, 98 patients with squamous cell carcinomas of the posterior pharyngeal wall were treated at the Curie Institute by radiotherapy alone. The absolute survival is 30% and 18% at three and five years. The major cause of death is loco-regional failure. 95% of the local failures arrived within the 18 first months. The 2 years control rate ranged from 80% for T1, 64% for T2, to 36% for T3 and 22% for T4. The local control is so depending on the radiation induced regression of the primary. The 2 years control rate is 71% for the patients with complete regression and 12% for the patients with not complete regression at the end of the treatment. The improvement of these results by adjunction of other treatments (surgery, chemotherapy, hyperthermia) is discussed.

摘要

1960年至1982年间,居里研究所仅采用放射疗法治疗了98例下咽后壁鳞状细胞癌患者。三年和五年的绝对生存率分别为30%和18%。主要死亡原因是局部区域复发。95%的局部复发发生在最初的18个月内。两年控制率从T1期的80%、T2期的64%,到T3期的36%和T4期的22%不等。局部控制情况取决于原发灶放疗后的退缩情况。治疗结束时,完全退缩患者的两年控制率为71%,未完全退缩患者的两年控制率为12%。文中还讨论了通过联合其他治疗方法(手术、化疗、热疗)改善这些结果的情况。

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