Kouyoumdjian J A, Tognola W A
Arq Neuropsiquiatr. 1985 Sep;43(3):296-302. doi: 10.1590/s0004-282x1985000300008.
A case of sarcosporidiosis in a 29 year-old woman is presented. The clinical picture showed a definitive myopathic pattern with symmetrical proximal weakness of shoulder and pelvic girdle and also weakness on neck flexors; the facial muscles were intact and she denied dysphagia. The histological findings after a muscle biopsy obtained from left deltoid muscle showed many round cysts within the muscle fibres without any surrounding inflammatory reaction. The cysts diameters varied from 30 to 500 micra and the length from 300 micra to 3 millimeter (Miescher's tube). The radially striated membrane could be seen in some cysts but there was some doubt because it could represent the remaining of the peripheral muscle fibre. We could not find spores inside the cysts. Besides the largest cysts there were muscle fibre hypertrophy. The authors concluded on the diagnosis of sarcosporidiosis because of the presence, diameter and length of cysts; some remarks are made on the only other parasite that could be confused with Sarcocystis sp: Toxoplasma gondii.
本文报告一例29岁女性的肉孢子虫病病例。临床表现为明确的肌病模式，肩部和骨盆带对称性近端肌无力，颈部屈肌也有肌无力；面部肌肉未受累，患者否认吞咽困难。取自左三角肌的肌肉活检组织学结果显示，肌纤维内有许多圆形囊肿，周围无任何炎症反应。囊肿直径从30微米到500微米不等，长度从300微米到3毫米（米舍尔管）。在一些囊肿中可见放射状条纹膜，但存在疑问，因为它可能代表外周肌纤维的残余部分。我们在囊肿内未发现孢子。除最大的囊肿外，还有肌纤维肥大。作者根据囊肿的存在、直径和长度得出肉孢子虫病的诊断结论；还对唯一可能与肉孢子虫混淆的另一种寄生虫：弓形虫进行了一些讨论。
