Dy Christopher J, Horowitz Roy S, Brogan David M
Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO, USA.
Department of Orthopedics, Hadassah Medical Center, Jerusalem, Israel.
J Hand Surg Asian Pac Vol. 2025 Feb;30(1):49-54. doi: 10.1142/S2424835525500043. Epub 2024 Oct 8.
Advances in treatment philosophies and microsurgical techniques for peripheral nerve injuries (PNI) have led to improved outcomes. However, lack of standardisation in the evaluation of clinical outcomes after PNI treatment precludes the ability to compare reconstruction methods, such as nerve transfer, nerve grafting, free functioning muscle transfers and tendon transfers. To this end, our goal is to work collaboratively to establish a core outcome set to evaluate outcomes after PNI. The protocol for this arc of work, delineated in this manuscript, consists of two phases: (1) conducting a systematic review of how outcomes are currently reported following PNI and (2) a Delphi process to gain consensus on the measures to include in the core outcome set for PNI. In the Delphi process, two online rounds will be used to gather consensus on the importance of each outcome measure. A final round will be conducted in person to discuss and resolve measures for which there is not yet consensus and to finalise the core outcomes set. Through this process, a common standard for reporting outcomes after PNI will be created, facilitating collaboration and future research.
外周神经损伤（PNI）治疗理念和显微外科技术的进步带来了更好的治疗效果。然而，PNI治疗后临床疗效评估缺乏标准化，这使得无法比较诸如神经移位、神经移植、游离功能性肌肉移植和肌腱移植等重建方法。为此，我们的目标是共同努力建立一个核心结局集，以评估PNI后的治疗效果。本手稿中描述的这一工作环节的方案包括两个阶段：（1）对PNI后目前如何报告治疗效果进行系统评价；（2）进行德尔菲法以就纳入PNI核心结局集的指标达成共识。在德尔菲法过程中，将通过两轮在线调查来就每个结局指标的重要性达成共识。最后一轮将进行面对面讨论，以讨论并解决尚未达成共识的指标，并最终确定核心结局集。通过这一过程，将创建一个报告PNI后治疗效果的通用标准，促进合作和未来研究。
