Tracking Magnesium Dynamics in Bell's Palsy: Correlations with Disease Progression and Recovery.

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This study investigates the relationship between serum magnesium levels and recovery outcomes in Bell's Palsy patients, aiming to elucidate magnesium's potential neuroprotective role in this condition. Conducted as a prospective cohort study at a tertiary care hospital, 50 Bell's Palsy patients had their serum magnesium levels measured at diagnosis and at 1 week, 1 month, 3 months, and 6 months post-diagnosis. Recovery was assessed using the House-Brackmann scale. The findings indicated an initial average serum magnesium level of 1.8 ± 0.3 mg/dL, increasing to 2.1 ± 0.3 mg/dL over six months. Higher baseline magnesium levels were significantly associated with improved recovery outcomes, with an Odds Ratio of 2.0 ( < 0.001). Longitudinal analysis revealed that increases in serum magnesium levels significantly correlated with improvements in the House-Brackmann grade ( < 0.001). These results suggest that rising serum magnesium levels are linked to better recovery in Bell's Palsy, advocating for further research into magnesium supplementation as a therapeutic strategy to enhance recovery in these patients.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12070-024-04796-4.