口腔套细胞淋巴瘤：罕见病例的鉴别显微镜诊断探索
Mantle Cell Lymphoma in the Oral Cavity: Exploring the Differential Microscopic Diagnosis of a Rare Case.
作者信息
Gonçalves Moisés Willian Aparecido, Lavareze Luccas, Chone Carlos Takahiro, Egal Erika Said Abu, Altemani Albina, Mariano Fernanda Viviane, de Freitas Leandro Luiz Lopes
机构信息
Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
Department of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
出版信息
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4806-4809. doi: 10.1007/s12070-024-04859-6. Epub 2024 Jul 3.
Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin's lymphoma (NHL), which generally has an aggressive course. Its pathophysiology seems to be related with the malignant transformation of B-cell mantle zone lymphocytes due to the rearrangement. The occurrence of MCL in the oral cavity is especially rare. In this report, we present an exceptional case of oral MCL diagnosed in the palate in a 56-year-old male patient, highlighting its distinct morphological and immunohistochemical features that may assist in the accurate diagnosis.
套细胞淋巴瘤（MCL）是B细胞非霍奇金淋巴瘤（NHL）的一种罕见亚型，通常病程侵袭性较强。其病理生理学似乎与B细胞套区淋巴细胞因重排而发生的恶性转化有关。MCL在口腔中发生尤为罕见。在本报告中，我们呈现了一例56岁男性患者腭部诊断为口腔MCL的特殊病例，突出了其独特的形态学和免疫组化特征，这些特征可能有助于准确诊断。
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