Guo Rongxia, Zhang Hao, Jiang Chenghui, Niu Chun, Chen Baoxia, Yuan Ziwen, Wei Yanming, Hua Yongli
Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China.
Front Vet Sci. 2024 Sep 23;11:1470158. doi: 10.3389/fvets.2024.1470158. eCollection 2024.
The objective of this study was to examine the impact of and extract (CA) on the growth performance, diarrhea rate, immune function, antioxidant capacity, gut microbiota, and short-chain fatty acids (SCFAs) in weaned piglets.
A total of forty-eight 31-day-old weaned piglets, were divided into four groups randomly based on the treatment type: control group (CON), low dose group (LCA, 0.5% CA), medium dose group (MCA, 1.0% CA), and high dose group (HCA, 1.5% CA), and were fed for a duration of 28 days. On the morning of the 1st and 29th day, the piglets were assessed by weighing them on an empty stomach, recording their daily feed intake and diarrhea rate.
CA increased the average daily weight gain and reduced F/G without significant differences, and the diarrhea rate was reduced in the LCA and MCA groups. Furthermore, the levels of T-AOC, SOD, GSH-Px, and MDA were increased. The levels of T-AOC in the LCA group and the MCA group, SOD in the MCA group, and GSH-Px in the HCA group were significantly higher compared with the CON group ( < 0.05). Additionally, CA significantly increased IgM, IgG, and IgA levels ( < 0.05). The results of gut microbiota analysis showed that the bacterial population and diversity of faeces were changed with the addition of CA to basal diets. CA increased the abundance of the beneficial bacterial Firmicutes and Lactobacillus. Additionally, Compared with the CON group, CA significantly increased the SCFAs content of weaned piglets ( < 0.05).
CA can alleviate oxidative stress, improve immunity and antioxidant capacity, increase the abundance of beneficial bacteria, and the content of SCFAs for improving the intestinal barrier of piglets, thus promoting growth and reducing diarrhea rate in weaned piglets.
本研究的目的是探讨[具体提取物名称]提取物（CA）对断奶仔猪生长性能、腹泻率、免疫功能、抗氧化能力、肠道微生物群和短链脂肪酸（SCFAs）的影响。
将48头31日龄断奶仔猪根据处理类型随机分为四组：对照组（CON）、低剂量组（LCA，0.5% CA）、中剂量组（MCA，1.0% CA）和高剂量组（HCA，1.5% CA），并饲养28天。在第1天和第29天上午，对仔猪进行空腹称重，记录其每日采食量和腹泻率。
CA提高了平均日增重并降低了料重比，但无显著差异，LCA组和MCA组腹泻率降低。此外，总抗氧化能力（T-AOC）、超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）和丙二醛（MDA）水平升高。LCA组和MCA组的T-AOC水平、MCA组的SOD水平以及HCA组的GSH-Px水平与CON组相比显著更高（P<0.05）。此外，CA显著提高了IgM、IgG和IgA水平（P<0.05）。肠道微生物群分析结果表明，在基础日粮中添加CA会改变粪便中的细菌种群和多样性。CA增加了有益菌厚壁菌门和乳酸杆菌的丰度。此外，与CON组相比，CA显著提高了断奶仔猪的SCFAs含量（P<0.05）。
CA可以减轻氧化应激，提高免疫力和抗氧化能力，增加有益菌的丰度以及SCFAs的含量，从而改善仔猪的肠道屏障，促进生长并降低断奶仔猪的腹泻率。
