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全基因组关联分析鉴定北京鸭胴体产量的候选基因。

Genome-wide association analysis identifies candidate genes for carcass yields in Peking ducks.

机构信息

National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing, China.

Beijing Nankou Duck Breeding Technology Ltd., Beijing, China.

出版信息

Anim Genet. 2024 Dec;55(6):833-837. doi: 10.1111/age.13480. Epub 2024 Oct 8.

DOI:10.1111/age.13480
PMID:39377540
Abstract

Poultry meat, particularly Peking ducks, holds a significant global market share, prized for their high meat yield and fat content. However, understanding of the molecular genetic mechanisms influencing carcass yield in ducks is limited. This research aims to use genome-wide association analysis to uncover single-nucleotide polymorphisms influencing carcass yield in Peking ducks, followed by identifying candidate genes linked to carcass traits. In this study, we analyzed seven traits of 643 Peking ducks at age 42 days and identified novel loci associated with these traits. A total of 35 significant loci were detected, with eight SNPs reaching genome-wide significance. KIF20B, AGBL5, SGSM1, MRO, PLAG1, XKR4, and TGS1 were considered as important candidate genes influencing carcass yield in ducks. This study adds to the list of genes affecting Peking duck body traits, aiding marker-assisted breeding and enhancing economic yield.

摘要

禽肉,尤其是北京烤鸭,在全球市场占据重要份额,因其出肉率和脂肪含量高而备受青睐。然而,我们对于影响鸭体产肉率的分子遗传机制的了解还很有限。本研究旨在利用全基因组关联分析,揭示影响北京鸭体产肉率的单核苷酸多态性,并鉴定与体躯性状相关的候选基因。在这项研究中,我们分析了 643 只 42 日龄北京鸭的 7 个体躯性状,鉴定出了与这些性状相关的新的基因座。共检测到 35 个显著基因座,其中 8 个 SNP 达到全基因组显著水平。KIF20B、AGBL5、SGSM1、MRO、PLAG1、XKR4 和 TGS1 被认为是影响鸭体产肉率的重要候选基因。本研究增加了影响北京鸭体躯性状的基因列表,有助于标记辅助选择和提高经济产量。

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