• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

ATP 结合盒转运蛋白 TaABCG2 通过介导小麦水杨酸的运输来参与赤霉病抗性。

ATP-binding cassette transporter TaABCG2 contributes to Fusarium head blight resistance by mediating salicylic acid transport in wheat.

机构信息

State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, Sichuan, China.

Triticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.

出版信息

Mol Plant Pathol. 2024 Oct;25(10):e70013. doi: 10.1111/mpp.70013.

DOI:10.1111/mpp.70013
PMID:39378008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11460253/
Abstract

ATP-binding cassette (ABC) transporters hydrolyse ATP to transport various substrates. Previous studies have shown that ABC transporters are responsible for transporting plant hormones and heavy metals, thus contributing to plant immunity. Herein, we identified a wheat G-type ABC transporter, TaABCG2-5B, that responds to salicylic acid (SA) treatment and is induced by Fusarium graminearum, the primary pathogen causing Fusarium head blight (FHB). The loss-of-function mutation of TaABCG2-5B (ΔTaabcg2-5B) reduced SA accumulation and increased susceptibility to F. graminearum. Conversely, overexpression of TaABCG2-5B (OE-TaABCG2-5B) exerted the opposite effect. Quantification of intracellular SA in ΔTaabcg2-5B and OE-TaABCG2-5B protoplasts revealed that TaABCG2-5B acts as an importer, facilitating the transport of SA into the cytoplasm. This role was further confirmed by Cd absorption experiments in wheat roots, indicating that TaABCG2-5B also participates in Cd transport. Thus, TaABCG2-5B acts as an importer and is crucial for transporting multiple substrates. Notably, the homologous gene TaABCG2-5A also facilitated Cd uptake in wheat roots but did not significantly influence SA accumulation or FHB resistance. Therefore, TaABCG2 could be a valuable target for enhancing wheat tolerance to Cd and improving FHB resistance.

摘要

三磷酸腺苷结合盒（ABC）转运蛋白通过水解三磷酸腺苷来转运各种底物。先前的研究表明，ABC 转运蛋白负责运输植物激素和重金属，从而有助于植物免疫。在此，我们鉴定了一个小麦 G 型 ABC 转运蛋白 TaABCG2-5B，它对水杨酸（SA）处理有反应，并被引起小麦赤霉病（FHB）的主要病原体禾谷镰刀菌诱导。TaABCG2-5B 的功能丧失突变（ΔTaabcg2-5B）减少了 SA 的积累并增加了对禾谷镰刀菌的敏感性。相反，TaABCG2-5B 的过表达（OE-TaABCG2-5B）则产生了相反的效果。ΔTaabcg2-5B 和 OE-TaABCG2-5B 原生质体中细胞内 SA 的定量表明 TaABCG2-5B 作为一种输入蛋白，促进 SA 向细胞质的运输。这一作用在小麦根中的 Cd 吸收实验中得到了进一步证实，表明 TaABCG2-5B 还参与 Cd 转运。因此，TaABCG2-5B 作为一种输入蛋白，对多种底物的运输至关重要。值得注意的是，同源基因 TaABCG2-5A 也促进了小麦根中的 Cd 吸收，但对 SA 积累或 FHB 抗性没有显著影响。因此，TaABCG2 可能是提高小麦对 Cd 耐受性和改善 FHB 抗性的有价值的靶标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/ad9d9b07137d/MPP-25-e70013-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/82bc392d57d0/MPP-25-e70013-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/f6505a4e89b9/MPP-25-e70013-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/5f269417c1bf/MPP-25-e70013-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/1ad5c399545a/MPP-25-e70013-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/8ae4e35ff85f/MPP-25-e70013-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/f0abd38991db/MPP-25-e70013-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/211e8455b090/MPP-25-e70013-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/ad9d9b07137d/MPP-25-e70013-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/82bc392d57d0/MPP-25-e70013-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/f6505a4e89b9/MPP-25-e70013-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/5f269417c1bf/MPP-25-e70013-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/1ad5c399545a/MPP-25-e70013-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/8ae4e35ff85f/MPP-25-e70013-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/f0abd38991db/MPP-25-e70013-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/211e8455b090/MPP-25-e70013-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6813/11460253/ad9d9b07137d/MPP-25-e70013-g001.jpg

相似文献

1
ATP-binding cassette transporter TaABCG2 contributes to Fusarium head blight resistance by mediating salicylic acid transport in wheat.ATP 结合盒转运蛋白 TaABCG2 通过介导小麦水杨酸的运输来参与赤霉病抗性。
Mol Plant Pathol. 2024 Oct;25(10):e70013. doi: 10.1111/mpp.70013.
2
Identification and differential induction of ABCG transporter genes in wheat cultivars challenged by a deoxynivalenol-producing Fusarium graminearum strain.在受产脱氧雪腐镰刀菌烯醇的禾谷镰刀菌菌株侵染的小麦品种中ABCG转运蛋白基因的鉴定与差异诱导
Mol Biol Rep. 2014 Sep;41(9):6181-94. doi: 10.1007/s11033-014-3497-7. Epub 2014 Jun 29.
3
Salicylic acid regulates basal resistance to Fusarium head blight in wheat.水杨酸调控小麦对赤霉病的基础抗性。
Mol Plant Microbe Interact. 2012 Mar;25(3):431-9. doi: 10.1094/MPMI-09-11-0232.
4
FgCWM1 modulates TaNDUFA9 to inhibit SA synthesis and reduce FHB resistance in wheat.FgCWM1 通过调节 TaNDUFA9 抑制 SA 合成并降低小麦对赤霉病的抗性。
BMC Biol. 2024 Sep 11;22(1):204. doi: 10.1186/s12915-024-02007-8.
5
ATP-Binding Cassette Transporter Gene Is Required for Its Transportation of Salicylic Acid, Fungicide Resistance, Mycelial Growth and Pathogenicity towards Wheat.三磷酸腺苷结合盒转运蛋白基因在其运输水杨酸、抗真菌剂抗性、菌丝生长和对小麦致病性中的作用。
Int J Mol Sci. 2018 Aug 10;19(8):2351. doi: 10.3390/ijms19082351.
6
Integrated transcriptome and hormone profiling highlight the role of multiple phytohormone pathways in wheat resistance against fusarium head blight.整合转录组和激素谱分析凸显了多种植物激素途径在小麦抗赤霉病中的作用。
PLoS One. 2018 Nov 7;13(11):e0207036. doi: 10.1371/journal.pone.0207036. eCollection 2018.
7
Identification of putative phosphoproteins in wheat spikes induced by Fusarium graminearum.禾谷镰刀菌诱导的小麦穗中假定磷酸化蛋白的鉴定
Planta. 2016 Mar;243(3):719-31. doi: 10.1007/s00425-015-2441-y. Epub 2015 Dec 15.
8
A wheat ABC transporter contributes to both grain formation and mycotoxin tolerance.一种小麦ABC转运蛋白对籽粒形成和霉菌毒素耐受性均有贡献。
J Exp Bot. 2015 May;66(9):2583-93. doi: 10.1093/jxb/erv048. Epub 2015 Mar 1.
9
Functional Analysis of Clarifies the Contribution of Salicylic Acid to Wheat () Resistance against Fusarium Head Blight.水杨酸对小麦（）赤霉病抗性的功能分析。
Toxins (Basel). 2019 Jan 22;11(2):59. doi: 10.3390/toxins11020059.
10
Effect of salicylic acid on Fusarium graminearum, the major causal agent of fusarium head blight in wheat.水杨酸对禾谷镰刀菌的影响，禾谷镰刀菌是小麦赤霉病的主要致病菌。
Fungal Biol. 2012 Mar;116(3):413-26. doi: 10.1016/j.funbio.2012.01.001. Epub 2012 Jan 16.

本文引用的文献

1
Natural resistance-associated macrophage proteins are involved in tolerance to heavy metal Cd toxicity and resistance to bacterial wilt of peanut (Arachis hypogaea L.).天然抗性相关巨噬细胞蛋白参与花生（Arachis hypogaea L.）对重金属镉毒性的耐受性及对青枯病的抗性。
Plant Physiol Biochem. 2024 Feb;207:108411. doi: 10.1016/j.plaphy.2024.108411. Epub 2024 Jan 30.
2
OsPDR20 is an ABCG metal transporter regulating cadmium accumulation in rice.OsPDR20 是一种 ABCG 金属转运蛋白，调节水稻中镉的积累。
J Environ Sci (China). 2024 Feb;136:21-34. doi: 10.1016/j.jes.2022.09.021. Epub 2022 Sep 24.
3
The TabHLH094-TaMYC8 complex mediates the cadmium response in wheat.
TabHLH094-TaMYC8复合物介导小麦中的镉响应。
Mol Breed. 2023 Jul 12;43(7):57. doi: 10.1007/s11032-023-01404-1. eCollection 2023 Jul.
4
Arabidopsis ABCG14 forms a homodimeric transporter for multiple cytokinins and mediates long-distance transport of isopentenyladenine-type cytokinins.拟南芥 ABCG14 形成同源二聚体转运蛋白，可转运多种细胞分裂素，并介导异戊烯基腺嘌呤型细胞分裂素的长距离运输。
Plant Commun. 2023 Mar 13;4(2):100468. doi: 10.1016/j.xplc.2022.100468. Epub 2022 Oct 28.
5
The rice heavy-metal transporter OsNRAMP1 regulates disease resistance by modulating ROS homoeostasis.水稻重金属转运蛋白OsNRAMP1通过调节活性氧稳态来调控抗病性。
Plant Cell Environ. 2022 Apr;45(4):1109-1126. doi: 10.1111/pce.14263. Epub 2022 Feb 3.
6
The gene TaWOX5 overcomes genotype dependency in wheat genetic transformation.基因 TaWOX5 克服了小麦遗传转化中的基因型依赖性。
Nat Plants. 2022 Feb;8(2):110-117. doi: 10.1038/s41477-021-01085-8. Epub 2022 Jan 13.
7
Cadmium toxicity in plants: Impacts and remediation strategies.植物中的镉毒性：影响与修复策略。
Ecotoxicol Environ Saf. 2021 Mar 15;211:111887. doi: 10.1016/j.ecoenv.2020.111887. Epub 2021 Jan 12.
8
The plant cuticle regulates apoplastic transport of salicylic acid during systemic acquired resistance.植物角质层在系统获得性抗性过程中调节水杨酸的质外体运输。
Sci Adv. 2020 May 6;6(19):eaaz0478. doi: 10.1126/sciadv.aaz0478. eCollection 2020 May.
9
The Effects of Cadmium Toxicity.镉毒性的影响。
Int J Environ Res Public Health. 2020 May 26;17(11):3782. doi: 10.3390/ijerph17113782.
10
Plant Immunity: Danger Perception and Signaling.植物免疫：危险感知与信号转导。
Cell. 2020 May 28;181(5):978-989. doi: 10.1016/j.cell.2020.04.028. Epub 2020 May 21.