Karasawa S
Nihon Seikeigeka Gakkai Zasshi. 1979 Nov;53(11):1579-94.
For the purpose of developing the ceramic artificial hip joint, we carried out biological and mechanical experiments. Tiny blocks of polycrystalline ceramic were inserted into the femurs of rabbits. Also, ceramic powder was injected into the knee joints of rabbits. Biological reaction were examined after varying intervals. It was proved, as a result, that ceramics have good affinity with living tissue. As a next step, wedge-shaped test pieces were inserted into the distal end of the femurs of dogs and tensile tests were carried out to investigate the degree of fixation of ceramic with bone. The result was that ceramic test pieces showed firmer fixation than those of metal. In the hip joints of five dogs, ceramic total hip prostheses for dogs were implanted. The dogs were autopsied after varying intervals and investigated histopathologically and scanning electron microscopically. Fixation of the socket and the prosthesis with the bone was superior to those made of metal and, moreover, virtually no wearing had taken place. However, the socket or prosthetic stems in four dogs were observed damaged in some parts. From the above mentioned, it is evident that when making ceramic total hip prostheses, we have to select ceramics of good quality and thicken their weightconcentrated parts by a device of its own design or use partly metal components coated with ceramic.
为了开发陶瓷人工髋关节,我们进行了生物学和力学实验。将多晶陶瓷小块插入兔子的股骨中。此外,将陶瓷粉末注入兔子的膝关节。在不同时间段后检查生物学反应。结果证明,陶瓷与活组织具有良好的亲和性。下一步,将楔形试件插入狗的股骨远端并进行拉伸试验,以研究陶瓷与骨的固定程度。结果是陶瓷试件比金属试件显示出更牢固的固定。在五只狗的髋关节中植入了狗用陶瓷全髋关节假体。在不同时间段后对狗进行解剖,并进行组织病理学和扫描电子显微镜检查。髋臼和假体与骨的固定优于金属制成的,而且几乎没有磨损发生。然而,观察到四只狗的髋臼或假体柄部分有损坏。从上述情况来看,很明显在制造陶瓷全髋关节假体时,我们必须选择质量好的陶瓷,并通过自行设计的装置加厚其重量集中部分,或者使用部分涂有陶瓷的金属部件。