Heimke G, Griss P, Jentschura G, Werner E
J Biomed Mater Res. 1979 Jan;13(1):57-65. doi: 10.1002/jbm.820130108.
The biocompatibility of high-purity dense Al2O3-ceramics had been shown to open the possibility of direct cement-free anchorage of joint endoprostheses. Three years of clinical experience with ceramic-metal composite total hip prostheses confirm the biomechanical design criteria used for the acetabular components. They also allow for additional conclusions regarding the reaction of bone tissue towards a bioinert implant. Further research activities are directed towards a solution for biomechanically stable anchorage of the femoral component of hip prostheses.