From the College of Medicine (Alturki, Jawa, Alghamdi, Althubiani, Bakhsh, Alqurashi), Department of Internal Medicine (Imam), Department of ophthalmology and ENT (Elhams), Vitreoretinal Surgeon, Eye Center (Algethami), Department of Physiology (Babateen), Faculty of Medicine, Umm Al Qura University, and from the Department of Neurology (Tawakul), Faculty of Medicine, Department of Medicine, Al-Abdia Main Campus, Makkah, Kingdom of Saudi Arabia.
Neurosciences (Riyadh). 2024 Oct;29(4):224-230. doi: 10.17712/nsj.2024.4.20230119.
To investigate the clinical results of optic neuritis (ON) patients in a tertiary medical facility in Makkah, Kingdom of Saudi Arabia.
The data of patients assessed for ON at Makkah, Saudi Arabia's King Abdullah Medical Center (KAMC), was examined retrospectively.
We identified 15 patients with ON. The ON was caused by multiple sclerosis (MS) in 73.3% of patients and neuromyelitis optica spectrum disorder (NMOSD) in 26.7% of patients. The disease was bilateral in 60% of patients and unilateral in 40% of patients. Additionally, 60% of patients had 2 or more episodes of ON, whereas 40% had a single episode. Patients with ON who presented with painful eye movements had a significantly longer disease duration (=0.032). Moreover, patients whose disease duration was 11-15 days did not achieve a complete resolution of their symptoms and experienced some residual vision loss compared to 30.8% who had continued visual changes (=0.049).
In the studied population, multiple sclerosis was the most prevalent cause of ON. Women were more likely to have ON. The prognosis for eyesight was substantially connected with the length of ON.
调查沙特阿拉伯麦加一家三级医疗机构视神经炎（ON）患者的临床结果。
回顾性分析沙特阿拉伯麦加阿卜杜拉国王医疗城（KAMC）评估 ON 患者的数据。
共纳入 15 例 ON 患者。73.3%的患者由多发性硬化症（MS）引起，26.7%的患者由视神经脊髓炎谱系疾病（NMOSD）引起。60%的患者为双侧 ON，40%的患者为单侧 ON。此外，60%的患者有 2 次或 2 次以上 ON 发作，40%的患者有 1 次发作。伴有疼痛性眼球运动的 ON 患者疾病持续时间显著较长（=0.032）。此外，疾病持续时间为 11-15 天的患者症状未完全缓解，与持续视力变化的 30.8%患者相比，视力丧失的比例更高（=0.049）。
在所研究的人群中，MS 是最常见的 ON 病因。女性更易发生 ON。视力预后与 ON 的持续时间密切相关。
