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改良 Koyanagi 术与分期 Duckett 术治疗近端型尿道下裂的比较研究。

Comparative study of modified Koyanagi and staged Duckett for proximal hypospadias.

机构信息

Department of Urology, Kunming Children's Hospital (Children's Hospital, Kunming Medical University), 288 Qianxing Road, Kunming, Yunnan, 650100, China.

Labortory Medicine Department, Kunming Children's Hospital (Children's Hospital, Kunming Medical University), 288 Qianxing Road, Kunming, Yunnan, 650100, China.

出版信息

BMC Urol. 2024 Oct 8;24(1):218. doi: 10.1186/s12894-024-01608-3.

DOI:10.1186/s12894-024-01608-3
PMID:39379882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11460186/
Abstract

AIM

To compare and analyze the clinical efficacy of modified Koyanagi and staged Duckett for proximal hypospadias.

METHOD

The clinical and prognostic data of children were treated and underwent surgery (modified Koyanagi or stage Duckett) in the Department of Urology, Kunming Children's Hospital from January 2020 to January 2023 were retrospectively analyzed. According to different surgical methods, the subjects were divided into the modified Koyanagi group and the staged Duckett group. Patients in both groups were followed up for more than 6 months after surgery. The success rate and complications of postoperative surgery in both groups were analyzed.

RESULT

A total of 63 patients were included in this study, 34 in the modified Koyanagi group and 29 in the staged Duckett group. A total of 14 patients in the modified Koyanagi group experienced postoperative complications, the success rate of the surgery was 58.82%, and 5 among them experienced more than two kinds of complications. A total of 5 children in the staging Duckett group experienced postoperative complications, and the success rate of the operation was 82.75%. There were significant differences in the incidence of overall complications and fistula between the two surgical methods (P = 0.028).

CONCLUSION

Compare with modified Koyanagi, staged Duckett can significantly reduce the incidence of overall complications and urethral fistula in patients, and have obvious advantages in the treatment of proximal hypospadias.

摘要

目的

比较分析改良 Koyanagi 术与分期 Duckett 术治疗近端尿道下裂的临床疗效。

方法

回顾性分析 2020 年 1 月至 2023 年 1 月在昆明市儿童医院泌尿外科接受手术(改良 Koyanagi 术或分期 Duckett 术)治疗的患儿的临床和预后资料。根据不同的手术方法,将患儿分为改良 Koyanagi 组和分期 Duckett 组。两组患儿术后均随访 6 个月以上。分析两组患儿术后手术成功率及并发症发生情况。

结果

本研究共纳入 63 例患儿,改良 Koyanagi 组 34 例,分期 Duckett 组 29 例。改良 Koyanagi 组 14 例患儿术后发生并发症,手术成功率为 58.82%,其中 5 例患儿发生两种以上并发症;分期 Duckett 组 5 例患儿术后发生并发症,手术成功率为 82.75%。两种手术方法的总并发症发生率和瘘管发生率比较,差异有统计学意义(P = 0.028)。

结论

与改良 Koyanagi 术相比,分期 Duckett 术能明显降低患儿总并发症和尿道瘘的发生率,在近端尿道下裂的治疗中具有明显优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e832/11460186/1d2774551360/12894_2024_1608_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e832/11460186/d2e771178ebb/12894_2024_1608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e832/11460186/1d2774551360/12894_2024_1608_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e832/11460186/d2e771178ebb/12894_2024_1608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e832/11460186/1d2774551360/12894_2024_1608_Fig2_HTML.jpg

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J Pediatr Urol. 2023 Dec;19(6):699.e1-699.e7. doi: 10.1016/j.jpurol.2023.07.018. Epub 2023 Aug 1.
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[Staged Duckett urethroplasty and Byars reconstruction for severe hypospadias with dysplastic glans].[分期行达克特尿道成形术及拜尔斯重建术治疗合并阴茎头发育异常的重度尿道下裂]
Zhonghua Nan Ke Xue. 2022 Feb;28(2):135-139.
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Repair of proximal hypospadias with single-stage (Duckett's method) or Bracka two-stage: a retrospective comparative cohort study.
单阶段(达克特法)或布拉卡两阶段修复近端尿道下裂:一项回顾性比较队列研究。
Transl Pediatr. 2023 Mar 31;12(3):387-395. doi: 10.21037/tp-23-75. Epub 2023 Mar 27.
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Urethral Plate Substitution in Two-Stage Hypospadias Repair: Grafts Versus Flaps.尿道板替代物在两阶段尿道下裂修复中的应用:移植物与皮瓣。
J Pediatr Surg. 2023 Oct;58(10):2027-2033. doi: 10.1016/j.jpedsurg.2023.03.006. Epub 2023 Mar 15.
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Preoperative hormone therapy in single-stage repair of hypospadias: A comprehensive systematic review.一期修复尿道下裂术前激素治疗:全面系统评价。
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